Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   CNZ63_RS04490 Genome accession   NZ_CP024232
Coordinates   855545..856168 (-) Length   207 a.a.
NCBI ID   WP_000122253.1    Uniprot ID   A0A370V1H3
Organism   Escherichia coli O6:H16 strain 2014EL-1346-6     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 850545..861168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CNZ63_RS04475 hupB 851122..851394 (-) 273 WP_001043542.1 nucleoid-associated protein HU-beta -
  CNZ63_RS04480 lon 851603..853957 (-) 2355 WP_001295325.1 endopeptidase La -
  CNZ63_RS04485 clpX 854145..855419 (-) 1275 WP_000130305.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  CNZ63_RS04490 clpP 855545..856168 (-) 624 WP_000122253.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  CNZ63_RS04495 tig 856414..857712 (-) 1299 WP_001198386.1 trigger factor -
  CNZ63_RS04505 bolA 858056..858373 (-) 318 WP_000973448.1 transcriptional regulator BolA -
  CNZ63_RS04515 yajG 858678..859256 (+) 579 WP_001295326.1 lipoprotein -
  CNZ63_RS04520 ampG 859300..860775 (+) 1476 WP_000098429.1 muropeptide MFS transporter AmpG -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23186.65 Da        Isoelectric Point: 5.6032

>NTDB_id=211680 CNZ63_RS04490 WP_000122253.1 855545..856168(-) (clpP) [Escherichia coli O6:H16 strain 2014EL-1346-6]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide


Download         Length: 624 bp        

>NTDB_id=211680 CNZ63_RS04490 WP_000122253.1 855545..856168(-) (clpP) [Escherichia coli O6:H16 strain 2014EL-1346-6]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGCGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG
CTAACCTGATTGTGGCGCAGATGCTCTTCCTGGAAGCGGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCCCCA
GGCGGGGTGATCACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGCTGACCGCAGGGGCAAAAGGTAAACGTTTTTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAACCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCCGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(26-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A370V1H3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

69.792

92.754

0.647
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.617

90.821

0.623
  clpP Lactococcus lactis subsp. cremoris KW2

56.701

93.72

0.531
  clpP Streptococcus pneumoniae R6

55.155

93.72

0.517
  clpP Streptococcus pneumoniae TIGR4

55.155

93.72

0.517
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

55.155

93.72

0.517
  clpP Streptococcus pneumoniae Rx1

55.155

93.72

0.517
  clpP Streptococcus pneumoniae D39

55.155

93.72

0.517
  clpP Streptococcus thermophilus LMD-9

54.922

93.237

0.512
  clpP Streptococcus thermophilus LMG 18311

54.922

93.237

0.512
  clpP Streptococcus pyogenes JRS4

55.263

91.787

0.507
  clpP Streptococcus pyogenes MGAS315

55.263

91.787

0.507
  clpP Streptococcus mutans UA159

53.886

93.237

0.502

Multiple sequence alignment