Detailed information NTG0211548

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: BUN12_RS13015
• Genome accession: NZ_CP018902
• Coordinates: 2488637..2489233 (+)
• Length: 198 a.a.
• NCBI ID: WP_003151513.1
• Uniprot ID: I2CAH7
• Organism: Bacillus amyloliquefaciens strain HK1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2483637..2494233

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUN12_RS12990 (BUN12_2549)	-	2483670..2483981 (+)	312	WP_013353708.1	hypothetical protein	-
BUN12_RS13000 (BUN12_2550)	-	2484292..2485761 (-)	1470	WP_013353709.1	glycoside hydrolase family 32 protein	-
BUN12_RS13005 (BUN12_2551)	-	2485776..2487008 (-)	1233	WP_013353710.1	MFS transporter	-
BUN12_RS13010 (BUN12_2552)	-	2487384..2488358 (+)	975	WP_013353711.1	LacI family DNA-binding transcriptional regulator	-
BUN12_RS13015 (BUN12_2553)	clpP	2488637..2489233 (+)	597	WP_003151513.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
BUN12_RS13020 (BUN12_2554)	-	2489276..2490136 (-)	861	WP_013353712.1	LysR family transcriptional regulator	-
BUN12_RS13025 (BUN12_2555)	-	2490308..2491438 (+)	1131	WP_013353713.1	2-methylaconitate cis-trans isomerase PrpF family protein	-
BUN12_RS13030 (BUN12_2556)	-	2491482..2492858 (+)	1377	WP_013353714.1	MFS transporter	-
BUN12_RS13035 (BUN12_2557)	-	2493041..2493880 (+)	840	WP_014471069.1	hypothetical protein	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21831.06 Da
• Isoelectric Point: 4.6982

>NTDB_id=211548 BUN12_RS13015 WP_003151513.1 2488637..2489233(+) (clpP) [Bacillus amyloliquefaciens strain HK1]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide

• Length: 597 bp

>NTDB_id=211548 BUN12_RS13015 WP_003151513.1 2488637..2489233(+) (clpP) [Bacillus amyloliquefaciens strain HK1]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGACATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCAAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCCATTTACATTAACAGCCCTGGCGGATCAATCACTGCCGGTATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTCTTACTTGCTGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTCATGATTCACCAGCCGCTTGGCGGAGCGCAAGGACAGGCGA
CTGAAATTGAAATCGCTGCTAAACGCATTCTCTTGCTTCGCGATAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTGATCGAGCGCGACACGGACCGCGACAACTTCAAATCAGCTGATGAAGCTTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACGGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: I2CAH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	95.96	100	0.96
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.586	96.465	0.662
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Streptococcus pneumoniae D39	57.216	97.98	0.561
clpP	Streptococcus pneumoniae Rx1	57.216	97.98	0.561
clpP	Streptococcus pneumoniae R6	57.216	97.98	0.561
clpP	Streptococcus pneumoniae TIGR4	57.216	97.98	0.561
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535
clpP	Streptococcus mutans UA159	54.639	97.98	0.535