Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   CO204_RS07350 Genome accession   NZ_CP023477
Coordinates   1444583..1445263 (-) Length   226 a.a.
NCBI ID   WP_002267104.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1439583..1450263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS07335 (CO204_07300) holA 1440339..1441379 (-) 1041 WP_019313137.1 DNA polymerase III subunit delta -
  CO204_RS07340 (CO204_07305) - 1441547..1442173 (-) 627 WP_002264731.1 DUF805 domain-containing protein -
  CO204_RS07345 (CO204_07310) comEC/celB 1442359..1444593 (-) 2235 WP_002267862.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CO204_RS07350 (CO204_07315) comEA/celA/cilE 1444583..1445263 (-) 681 WP_002267104.1 helix-hairpin-helix domain-containing protein Machinery gene
  CO204_RS07355 (CO204_07320) - 1445403..1446155 (-) 753 WP_002264733.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  CO204_RS07360 (CO204_07325) - 1446294..1447229 (+) 936 WP_019313136.1 polysaccharide deacetylase family protein -
  CO204_RS07365 (CO204_07330) - 1447318..1447830 (+) 513 WP_002261919.1 HXXEE domain-containing protein -
  CO204_RS07370 (CO204_07335) - 1447876..1448895 (+) 1020 WP_019313135.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24558.90 Da        Isoelectric Point: 8.2999

>NTDB_id=207453 CO204_RS07350 WP_002267104.1 1444583..1445263(-) (comEA/celA/cilE) [Streptococcus mutans strain LAR01]
MVDEFLDKLKEKKNVFALVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQVTTAKSTITVDIK
GAVKHEGVYTLPIDSRINDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETS
VKGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVDDLKNISGIGDKTFEKLKDLVSVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=207453 CO204_RS07350 WP_002267104.1 1444583..1445263(-) (comEA/celA/cilE) [Streptococcus mutans strain LAR01]
ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATGTTTTTGCCCTAGTTGGTGGTCTTGTAGTCTTACTGGG
TCTGGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGATAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG
TAACCACAAAGACTGGCAAAGAAAGTCAAAAGAAGACGCAGGTGACGACTGCCAAATCAACAATAACTGTTGATATTAAA
GGAGCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTAATGATGTAATAGAAAAAGCGGGAGGTTT
TTCTGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTG
GTGAGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTCG
GTAAAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCA
GGATATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGGATGATTTGAAAAATATTTCAGGGATTGGCGATA
AAACATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(163-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.489

100

0.438
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.06

100

0.434
  comEA/celA/cilE Streptococcus mitis SK321

42.241

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae D39

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae Rx1

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae R6

41.631

100

0.429
  comEA Lactococcus lactis subsp. cremoris KW2

42.478

100

0.425
  comEA Streptococcus thermophilus LMD-9

57.143

68.142

0.389
  comEA Latilactobacillus sakei subsp. sakei 23K

35.537

100

0.381