Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR1   Type   Regulator
Locus tag   SPG_2028 Genome accession   CP001015
Coordinates   1913557..1913937 (-) Length   126 a.a.
NCBI ID   ACF56257.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1908557..1918937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_2022 - 1908807..1909682 (+) 876 ACF56193.1 ABC transporter, binding protein -
  SPG_2023 - 1909800..1910663 (+) 864 ACF55807.1 ABC transporter, permease protein -
  SPG_2024 - 1910656..1911471 (+) 816 ACF55204.1 ABC transporter, permease protein -
  SPG_2025 - 1911473..1912225 (+) 753 ACF56636.1 ABC transporter, ATP-binding protein -
  SPG_2026 - 1912240..1912890 (+) 651 ACF56575.1 phosphate transport system regulatory protein -
  SPG_2027 - 1912958..1913383 (+) 426 ACF55778.1 IS1380-Spn1, transposase -
  SPG_2028 comR/comR1 1913557..1913937 (-) 381 ACF56257.1 hypothetical protein Regulator
  SPG_2029 gpsA 1914149..1915165 (+) 1017 ACF56426.1 NAD-dependent glycerol-3-phosphate dehydrogenase -
  SPG_2030 galU 1915187..1916086 (+) 900 ACF55268.1 UTP-glucose-1-phosphate uridylyltransferase -
  SPG_2031 - 1916153..1916830 (-) 678 ACF55494.1 peptidase, S54 (rhomboid) family protein -
  SPG_2032 - 1916814..1917353 (-) 540 ACF55981.1 5-formyltetrahydrofolate cyclo-ligase family protein -
  SPG_2033 - 1917365..1918495 (-) 1131 ACF55104.1 Peptidase family M20/M25/M40 -

Sequence

Protein


Download         Length: 126 a.a.        Molecular weight: 15119.73 Da        Isoelectric Point: 9.7045

>NTDB_id=20419 SPG_2028 ACF56257.1 1913557..1913937(-) (comR/comR1) [Streptococcus pneumoniae G54]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVLIRFLKSIMIGYLRKKDLSSQIIHIWH

Nucleotide


Download         Length: 381 bp        

>NTDB_id=20419 SPG_2028 ACF56257.1 1913557..1913937(-) (comR/comR1) [Streptococcus pneumoniae G54]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGTTGAGGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTGATAAGATTTTTGAAGAGTAT
TATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTGGCACTAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(8-59)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.085

100

0.421
  comR Streptococcus pyogenes MGAS315

52.041

77.778

0.405
  comR Streptococcus pyogenes MGAS8232

52.041

77.778

0.405
  comR Streptococcus mutans UA159

51.515

78.571

0.405
  comR Streptococcus suis D9

47.475

78.571

0.373
  comR Streptococcus suis P1/7

47.475

78.571

0.373
  comR Streptococcus suis 05ZYH33

47.475

78.571

0.373
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.809

70.635

0.373

Multiple sequence alignment