Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SMA_1570 Genome accession   HE613569
Coordinates   1540265..1540975 (-) Length   236 a.a.
NCBI ID   CCF02861.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1535265..1545975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_1566 rnc 1536923..1537609 (-) 687 CCF02857.1 Ribonuclease III -
  SMA_1567 - 1537893..1538021 (-) 129 CCF02858.1 Hypothetical protein -
  SMA_1568 vicX 1538110..1538919 (-) 810 CCF02859.1 Zn-dependent hydrolase (beta-lactamase superfamily) Regulator
  SMA_1569 vicK 1538920..1540272 (-) 1353 CCF02860.1 Two-component sensor kinase SA14-24 Regulator
  SMA_1570 vicR 1540265..1540975 (-) 711 CCF02861.1 Two-component response regulator SA14-24 Regulator
  SMA_1571 - 1541280..1542044 (+) 765 CCF02862.1 Glutamate transport ATP-binding protein -
  SMA_1572 - 1542055..1542867 (+) 813 CCF02863.1 Amino acid ABCtransporter substrate-binding protein -
  SMA_1573 - 1542884..1543588 (+) 705 CCF02864.1 Amino acid ABC transporter permease -
  SMA_1574 - 1543600..1544247 (+) 648 CCF02865.1 Amino acid ABC transporter integral membrane protein -
  SMA_1575 - 1544339..1544947 (-) 609 CCF02866.1 Hypothetical protein -
  SMA_1576 - 1545195..1545497 (-) 303 CCF02867.1 Hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27116.91 Da        Isoelectric Point: 4.6512

>NTDB_id=20361 SMA_1570 CCF02861.1 1540265..1540975(-) (vicR) [Streptococcus macedonicus ACA-DC 198]
MKKILIVDDEKPISDIIKFNLTKEGYEAITAFDGREAITKFEEEDPDLIILDLMLPELDGLEVAKEVRKTSHIPIIILSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEENASASNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=20361 SMA_1570 CCF02861.1 1540265..1540975(-) (vicR) [Streptococcus macedonicus ACA-DC 198]
ATGAAAAAAATTCTTATCGTTGATGATGAAAAACCAATTTCGGATATTATTAAATTTAATTTAACTAAAGAGGGTTATGA
AGCCATAACGGCTTTTGATGGTCGTGAAGCTATTACAAAGTTTGAGGAAGAAGACCCAGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGACGGACTTGAAGTGGCTAAAGAAGTTCGCAAGACAAGTCATATTCCAATCATTATATTGTCTGCT
AAGGATAGCGAGTTTGATAAAGTTATCGGACTTGAAATCGGTGCAGATGACTATGTAACCAAACCATTTTCAAATCGTGA
ATTGTTGGCGCGTGTTAAAGCGCACCTTCGTCGTACAGAAAATATTGAAACAGCAGTTGCTGAAGAAAATGCTTCTGCTT
CAAATTCAGAAATCACAATTGGTGACTTGAAAATCTTACCAGACGCCTTTGTGGCACAAAAACGTGGTGAAGATATCGAA
TTAACACACCGTGAGTTTGAATTGCTTCATCATTTGGCAACACATATGGGACAAGTCATGACCCGTGAATATCTTTTGGA
AACCGTTTGGGGCTATGATTATTTTGGTGATGTGCGTACGGTTGACGTAACCATTCGTCGTTTACGTGAAAAAATCGAAG
ACACACCAAGCCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGGTACTACATGAAGTCATATGAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.407

100

0.894
  micA Streptococcus pneumoniae Cp1015

76.923

99.153

0.763
  covR Streptococcus salivarius strain HSISS4

46.983

98.305

0.462
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.259

98.305

0.445
  scnR Streptococcus mutans UA159

37.288

100

0.373

Multiple sequence alignment