Detailed information NTG0020360

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: SMA_1569
• Genome accession: HE613569
• Coordinates: 1538920..1540272 (-)
• Length: 450 a.a.
• NCBI ID: CCF02860.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus ACA-DC 198
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1533920..1545272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMA_1566	rnc	1536923..1537609 (-)	687	CCF02857.1	Ribonuclease III	-
SMA_1567	-	1537893..1538021 (-)	129	CCF02858.1	Hypothetical protein	-
SMA_1568	vicX	1538110..1538919 (-)	810	CCF02859.1	Zn-dependent hydrolase (beta-lactamase superfamily)	Regulator
SMA_1569	vicK	1538920..1540272 (-)	1353	CCF02860.1	Two-component sensor kinase SA14-24	Regulator
SMA_1570	vicR	1540265..1540975 (-)	711	CCF02861.1	Two-component response regulator SA14-24	Regulator
SMA_1571	-	1541280..1542044 (+)	765	CCF02862.1	Glutamate transport ATP-binding protein	-
SMA_1572	-	1542055..1542867 (+)	813	CCF02863.1	Amino acid ABCtransporter substrate-binding protein	-
SMA_1573	-	1542884..1543588 (+)	705	CCF02864.1	Amino acid ABC transporter permease	-
SMA_1574	-	1543600..1544247 (+)	648	CCF02865.1	Amino acid ABC transporter integral membrane protein	-
SMA_1575	-	1544339..1544947 (-)	609	CCF02866.1	Hypothetical protein	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51553.66 Da
• Isoelectric Point: 4.7361

>NTDB_id=20360 SMA_1569 CCF02860.1 1538920..1540272(-) (vicK) [Streptococcus macedonicus ACA-DC 198]
MNDTMLQNLTYFEQAILFLLAFVAVYFVYLAIREYQTSANIRRLSGKVRELITGKYTEDIIIEKDRDLAELADQLNDLSK
VFRLAQENLAQEKNRLASILSYMTDGVLATDRAGNIIMINQTAQQQLNLEREEALQMNIVDILGSDSTYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPNFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTISGKQYEIVRNYPIKP
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSEIYDEWEDEEE

Nucleotide

• Length: 1353 bp

>NTDB_id=20360 SMA_1569 CCF02860.1 1538920..1540272(-) (vicK) [Streptococcus macedonicus ACA-DC 198]
ATGAATGATACAATGTTACAAAATTTAACTTATTTTGAACAAGCCATTCTCTTTCTTTTAGCATTTGTCGCAGTTTATTT
TGTTTATTTAGCGATAAGAGAATATCAAACTTCTGCTAATATTCGCCGTTTGAGTGGTAAAGTGCGAGAGCTTATCACAG
GAAAATACACAGAAGATATTATTATTGAAAAAGATAGAGACTTAGCTGAGTTAGCTGATCAATTAAATGATTTGTCAAAA
GTCTTTCGTTTAGCGCAGGAAAATTTGGCACAAGAAAAGAATCGTTTGGCGAGTATCTTATCTTATATGACAGACGGTGT
CTTGGCGACTGACCGTGCTGGAAATATCATAATGATAAATCAGACCGCGCAACAACAACTCAATTTAGAGCGTGAAGAAG
CTTTGCAGATGAATATTGTTGATATTTTGGGTTCTGATAGCACTTATAGTTATCATGATTTGGTGTCAAAAACACCTGAA
ATTGTCTTGAACCGTCGTGACGAAACAGGTGAATTTATCACTTTACGTATTCGCTTTGCTCTAAATCGTCGTGATAGTGG
TTTTATTTCAGGGTTGATTGCCGTTTTGCATGACACAACCGAACAAGAGAAAGAAGACCGTGAGCGTCGTCTTTTCGTTT
CTAACGTTAGTCATGAATTGCGAACACCATTAACATCTGTAAAATCTTATCTGGAAGCCTTAGATGAAGGAGCGCTCAAA
GAAGACATTGCGCCAAATTTTATCAAAGTATCTTTAGATGAAACAAACCGCATGATTCGTATGATTTCAGACTTGCTTAA
TTTATCGCGTATTGATAATCAGACGGTTCAATTGGAAGTGGAAATGACAAATTTCACAGCATTTATGACATCAATTCTTA
ACCGTTTTGATCAAATTAAAAGCCAACATACAATCAGCGGAAAACAGTATGAGATTGTCAGGAATTATCCTATTAAACCA
ATCTGGCTTGAAATTGATCCTGATAAGATGACGCAGGTTTTGGATAATATCCTTAATAATGCTATCAAATATTCACCAGA
TGGTGGAAAAATCACAGTTAGCATGAAAACGACGGAAACACAGTTGATTATCTCAATCTCTGATGAAGGGCTTGGTATTC
CTAAGAAAGATTTGCCATTGATTTTCGACCGTTTCTACCGTGTGGATAAGGCTCGAAGTCGTGCCCAAGGTGGTTCAGGA
CTTGGCTTAGCTATCGCAAAAGAAATTGTCAAACAACATAAAGGTTTTATTTGGGCACAAAGTACTTACGGAAAAGGGTC
GACCTTTACGATTGTACTTCCTTACGAAAAAGATTCTGAAATTTATGATGAATGGGAGGATGAAGAAGAGTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-189)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	74.94	92.222	0.691
micB	Streptococcus pneumoniae Cp1015	65.566	94.222	0.618