Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   BG256_RS04170 Genome accession   NZ_CP017811
Coordinates   849267..850604 (-) Length   445 a.a.
NCBI ID   WP_071162872.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NML-Hia-1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 844267..855604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BG256_RS04145 (BG256_04145) - 845996..846268 (-) 273 WP_005630954.1 HU family DNA-binding protein -
  BG256_RS04150 (BG256_04150) - 846408..846998 (-) 591 WP_071162869.1 YjaG family protein -
  BG256_RS04155 (BG256_04155) nudC 847034..847828 (-) 795 WP_071162870.1 NAD(+) diphosphatase -
  BG256_RS04160 (BG256_04160) nfuA 847896..848492 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  BG256_RS04165 (BG256_04165) - 848568..849254 (-) 687 WP_071162871.1 ComF family protein -
  BG256_RS04170 (BG256_04170) comE 849267..850604 (-) 1338 WP_071162872.1 type IV pilus secretin PilQ family protein Machinery gene
  BG256_RS04175 (BG256_04175) comD 850614..851027 (-) 414 WP_005693727.1 pilus assembly protein PilP Machinery gene
  BG256_RS04180 (BG256_04180) comC 851024..851545 (-) 522 WP_048951462.1 competence protein ComC Machinery gene
  BG256_RS04185 (BG256_04185) comB 851542..852048 (-) 507 WP_071162873.1 competence protein ComB Machinery gene
  BG256_RS04190 (BG256_04190) comA 852049..852846 (-) 798 WP_071162874.1 competence protein ComA Machinery gene
  BG256_RS04195 (BG256_04195) - 852944..855538 (+) 2595 WP_071162875.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49155.39 Da        Isoelectric Point: 7.4788

>NTDB_id=203127 BG256_RS04170 WP_071162872.1 849267..850604(-) (comE) [Haemophilus influenzae strain NML-Hia-1]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGIYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGEK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=203127 BG256_RS04170 WP_071162872.1 849267..850604(-) (comE) [Haemophilus influenzae strain NML-Hia-1]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGATTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCTTTAACAACAGGAAGTGGATCTTTGCTTTCTCCTGCGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCGGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGGAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.876

100

0.989
  comE Haemophilus influenzae Rd KW20

98.202

100

0.982
  comE Glaesserella parasuis strain SC1401

52.471

95.506

0.501
  pilQ Vibrio campbellii strain DS40M4

42.721

94.157

0.402
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.99

92.584

0.389
  pilQ Vibrio cholerae strain A1552

41.99

92.584

0.389

Multiple sequence alignment