Detailed information NTG0020199

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SPG_1160
• Genome accession: CP001015
• Coordinates: 1133991..1134839 (-)
• Length: 282 a.a.
• NCBI ID: ACF56253.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae G54
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1128991..1139839

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPG_1154	-	1129112..1129252 (-)	141	ACF55865.1	copper homeostasis protein CutC	-
SPG_1155	-	1129345..1129704 (-)	360	ACF56664.1	conserved hypothetical protein	-
SPG_1156	topA	1129810..1131897 (-)	2088	ACF54979.1	DNA topoisomerase I	-
SPG_1157	-	1132064..1133083 (-)	1020	ACF55153.1	conserved hypothetical protein	-
SPG_1158	-	1133007..1133141 (+)	135	ACF55567.1	hypothetical protein	-
SPG_1159	-	1133651..1133893 (-)	243	ACF56861.1	hypothetical protein	-
SPG_1160	dprA/cilB/dalA	1133991..1134839 (-)	849	ACF56253.1	DNA processing Smf protein	Machinery gene
SPG_1161	-	1134925..1135614 (-)	690	ACF56224.1	CTP:phosphocholine cytidylyltransferase	-
SPG_1162	-	1135626..1136504 (-)	879	ACF55604.1	licB protein	-
SPG_1163	-	1136494..1137363 (-)	870	ACF55152.1	choline kinase	-
SPG_1164	-	1137380..1138402 (-)	1023	ACF56026.1	alcohol dehydrogenase, zinc-dependent	-
SPG_1165	-	1138407..1139114 (-)	708	ACF54889.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31062.72 Da
• Isoelectric Point: 5.4047

>NTDB_id=20199 SPG_1160 ACF56253.1 1133991..1134839(-) (dprA/cilB/dalA) [Streptococcus pneumoniae G54]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=20199 SPG_1160 ACF56253.1 1133991..1134839(-) (dprA/cilB/dalA) [Streptococcus pneumoniae G54]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAATCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	100	100	1
dprA/cilB/dalA	Streptococcus pneumoniae D39	100	100	1
dprA/cilB/dalA	Streptococcus pneumoniae R6	100	100	1
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	100	100	1
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.582	100	0.986
dprA/cilB/dalA	Streptococcus mitis SK321	97.872	100	0.979
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553
dprA	Staphylococcus aureus N315	37.809	100	0.379
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362