Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SPG_1118 Genome accession   CP001015
Coordinates   1095703..1096407 (-) Length   234 a.a.
NCBI ID   ACF56101.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1090703..1101407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_1112 ldh 1090896..1091882 (+) 987 ACF56088.1 L-lactate dehydrogenase -
  SPG_1113 - 1092171..1092914 (-) 744 ACF56454.1 transporter, cation channel family -
  SPG_1114 - 1092961..1093215 (-) 255 ACF55143.1 hypothetical protein -
  SPG_1115 - 1093217..1093459 (-) 243 ACF55454.1 conserved hypothetical protein -
  SPG_1116 vicX 1093550..1094359 (-) 810 ACF55780.1 VicX protein Regulator
  SPG_1117 micB 1094361..1095710 (-) 1350 ACF56485.1 histidine kinase TCS02 Regulator
  SPG_1118 micA 1095703..1096407 (-) 705 ACF56101.1 response regulator TCS02 Regulator
  SPG_1119 mutY 1096463..1097638 (-) 1176 ACF55665.1 A/G-specific adenine glycosylase -
  SPG_1120 fhs 1097966..1099636 (-) 1671 ACF55434.1 formate--tetrahydrofolate ligase -
  SPG_1121 coaB 1099866..1100555 (+) 690 ACF55021.1 phosphopantothenate--cysteine ligase -
  SPG_1122 coaC 1100567..1101118 (+) 552 ACF56444.1 phosphopantothenoylcysteine decarboxylase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=20198 SPG_1118 ACF56101.1 1095703..1096407(-) (micA) [Streptococcus pneumoniae G54]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=20198 SPG_1118 ACF56101.1 1095703..1096407(-) (micA) [Streptococcus pneumoniae G54]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment