Detailed information NTG0020197

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: SPG_1117
• Genome accession: CP001015
• Coordinates: 1094361..1095710 (-)
• Length: 449 a.a.
• NCBI ID: ACF56485.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae G54
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1089361..1100710

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPG_1112	ldh	1090896..1091882 (+)	987	ACF56088.1	L-lactate dehydrogenase	-
SPG_1113	-	1092171..1092914 (-)	744	ACF56454.1	transporter, cation channel family	-
SPG_1114	-	1092961..1093215 (-)	255	ACF55143.1	hypothetical protein	-
SPG_1115	-	1093217..1093459 (-)	243	ACF55454.1	conserved hypothetical protein	-
SPG_1116	vicX	1093550..1094359 (-)	810	ACF55780.1	VicX protein	Regulator
SPG_1117	micB	1094361..1095710 (-)	1350	ACF56485.1	histidine kinase TCS02	Regulator
SPG_1118	micA	1095703..1096407 (-)	705	ACF56101.1	response regulator TCS02	Regulator
SPG_1119	mutY	1096463..1097638 (-)	1176	ACF55665.1	A/G-specific adenine glycosylase	-
SPG_1120	fhs	1097966..1099636 (-)	1671	ACF55434.1	formate--tetrahydrofolate ligase	-
SPG_1121	coaB	1099866..1100555 (+)	690	ACF55021.1	phosphopantothenate--cysteine ligase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51688.43 Da
• Isoelectric Point: 4.9098

>NTDB_id=20197 SPG_1117 ACF56485.1 1094361..1095710(-) (micB) [Streptococcus pneumoniae G54]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSLLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide

• Length: 1350 bp

>NTDB_id=20197 SPG_1117 ACF56485.1 1094361..1095710(-) (micB) [Streptococcus pneumoniae G54]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAATGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGAGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCTCCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (98-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	99.555	100	0.996
vicK	Streptococcus mutans UA159	69.652	89.532	0.624