Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SPG_0877 Genome accession   CP001015
Coordinates   848143..848793 (+) Length   216 a.a.
NCBI ID   ACF55568.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 843143..853793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_0871 pyrH 843867..844604 (+) 738 ACF56203.1 uridylate kinase -
  SPG_0872 - 844613..845170 (+) 558 ACF55740.1 ribosome recycling factor -
  SPG_0873 - 845191..846084 (+) 894 ACF56821.1 conserved hypothetical protein -
  SPG_0874 - 846093..846308 (+) 216 ACF56370.1 conserved domain protein -
  SPG_0875 - 846394..847398 (+) 1005 ACF55319.1 PhoH family protein -
  SPG_0876 - 847506..848075 (+) 570 ACF54920.1 acetyltransferase, GNAT family protein -
  SPG_0877 comEA/celA/cilE 848143..848793 (+) 651 ACF55568.1 competence protein (ComEA) Machinery gene
  SPG_0878 comEC/celB 848777..851017 (+) 2241 ACF55096.1 competence protein (comEC) Machinery gene
  SPG_0879 - 851238..851384 (+) 147 ACF55705.1 conserved hypothetical protein -
  SPG_0880 - 851416..852003 (+) 588 ACF55235.1 ABC transporter, ATP-binding protein -
  SPG_0881 - 852007..853167 (+) 1161 ACF56678.1 hypothetical protein -
  SPG_0882 - 853206..853340 (-) 135 ACF56182.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23180.30 Da        Isoelectric Point: 5.5171

>NTDB_id=20192 SPG_0877 ACF55568.1 848143..848793(+) (comEA/celA/cilE) [Streptococcus pneumoniae G54]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAXKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=20192 SPG_0877 ACF55568.1 848143..848793(+) (comEA/celA/cilE) [Streptococcus pneumoniae G54]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTNAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae D39

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae R6

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.759

100

0.968
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis SK321

90.741

100

0.907
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366

Multiple sequence alignment