Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   Spy49_0980c Genome accession   CP000829
Coordinates   973697..974371 (-) Length   224 a.a.
NCBI ID   ACI61280.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 968697..979371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_0975c cdd 969144..969533 (-) 390 ACI61275.1 Cytidine deaminase -
  Spy49_0976c - 970186..970779 (-) 594 ACI61276.1 Conserved hypothetical protein -
  Spy49_0977 coaA 971047..971967 (+) 921 ACI61277.1 Pantothenate kinase -
  Spy49_0978 prsT 972036..972269 (+) 234 ACI61278.1 SSU ribosomal protein S20p -
  Spy49_0979c ciaH 972394..973704 (-) 1311 ACI61279.1 Putative histidine kinase protein Regulator
  Spy49_0980c ciaR 973697..974371 (-) 675 ACI61280.1 Transcriptional regulatory protein ciaR Regulator
  Spy49_0981c pepN 974718..977255 (-) 2538 ACI61281.1 Putative lysyl-aminopeptidase -
  Spy49_0982c phoU 977460..978113 (-) 654 ACI61282.1 Putative phosphate uptake regulatory protein -
  Spy49_0983c pstB 978182..978940 (-) 759 ACI61283.1 Phosphate transport ATP-binding protein pstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25703.91 Da        Isoelectric Point: 4.7287

>NTDB_id=20149 Spy49_0980c ACI61280.1 973697..974371(-) (ciaR) [Streptococcus pyogenes NZ131]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGYILKNNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=20149 Spy49_0980c ACI61280.1 973697..974371(-) (ciaR) [Streptococcus pyogenes NZ131]
ATGATAAAAATATTATTAGTAGAAGATGACTTGAGCTTATCAAATTCCATTTTTGATTTTTTAGATGATTTTGCAGACGT
CATGCAAGTTTTTGATGGCGATGAAGGTTTATACGAAGCAGAAAGTGGTATTTATGATTTGATTTTGTTAGACCTTATGT
TGCCGGAGAAAAATGGCTTTCAAGTCTTAAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATCATGACAGCT
AAAGAGGGTTTAGATGATAAAGGTCACGGATTTGAATTAGGTGCTGATGATTATCTGACCAAGCCGTTCTATTTAGAAGA
GTTAAAAATGCGAATTCAAGCACTGTTAAAAAGAACAGGGAAATTTGCAGATAAAAATATTAGTTTTGGCAATTTAGTGG
TCGACTTAGCTCGAAAAGAGGTGAAGGTTGAAGGGAAAGTAGTTGAATTACTTGGCAAAGAATTTGATTTGTTGGTGTAT
CTTTTGCAAAATCAAAACGTTATTTTACCAAAGACACAAATTTTTGATCGTTTATGGGGATTCGATAGTGATACTACGAT
TTCGGTTGTTGAAGTTTACATTTCTAAAATAAGGAAAAAATTAAAAGGTACCCGTTTTGTTAACAGGCTTCAAACTTTAA
GAAGCGTAGGGTATATTCTAAAAAACAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

85.135

99.107

0.844
  ciaR Streptococcus pneumoniae D39

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae R6

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae TIGR4

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae Rx1

84.685

99.107

0.839
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.111

100

0.393
  vicR Streptococcus mutans UA159

35.897

100

0.375
  micA Streptococcus pneumoniae Cp1015

35.47

100

0.371
  covR Streptococcus salivarius strain HSISS4

36.283

100

0.366

Multiple sequence alignment