Detailed information NTG0201354

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BKM67_RS04690
• Genome accession: NZ_CP017667
• Coordinates: 928538..929209 (+)
• Length: 223 a.a.
• NCBI ID: WP_112477650.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1081
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 923538..934209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKM67_RS04660 (BKM67_04565)	pstC	923595..924512 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
BKM67_RS04665 (BKM67_04570)	pstA	924502..925389 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
BKM67_RS04670 (BKM67_04575)	pstB	925414..926217 (+)	804	WP_112477648.1	phosphate ABC transporter ATP-binding protein PstB	-
BKM67_RS04675 (BKM67_04580)	pstB	926229..926987 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
BKM67_RS04680 (BKM67_04585)	phoU	927016..927672 (+)	657	WP_112477649.1	phosphate signaling complex protein PhoU	-
BKM67_RS04685 (BKM67_04590)	-	927838..928344 (+)	507	WP_024385292.1	hypothetical protein	-
BKM67_RS04690 (BKM67_04595)	ciaR	928538..929209 (+)	672	WP_112477650.1	response regulator transcription factor	Regulator
BKM67_RS04695 (BKM67_04600)	ciaH	929202..930581 (+)	1380	WP_112477651.1	HAMP domain-containing sensor histidine kinase	Regulator
BKM67_RS04700 (BKM67_04605)	-	930682..931911 (+)	1230	WP_112477652.1	transglutaminase domain-containing protein	-
BKM67_RS04705 (BKM67_04610)	rpsT	932174..932422 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
BKM67_RS04710 (BKM67_04615)	coaA	932481..933401 (-)	921	WP_002935283.1	type I pantothenate kinase	-
BKM67_RS04715 (BKM67_04620)	-	933510..934100 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25253.85 Da
• Isoelectric Point: 4.3008

>NTDB_id=201354 BKM67_RS04690 WP_112477650.1 928538..929209(+) (ciaR) [Streptococcus suis strain 1081]
MIKILLVEDDLSLSNSVFDFLHDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=201354 BKM67_RS04690 WP_112477650.1 928538..929209(+) (ciaR) [Streptococcus suis strain 1081]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGCCTATCAAATTCTGTTTTCGATTTCTTACATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACCCCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTGAAACGAGCGGGTAAGTTTAATGAAAACACACTAACTTATGGGGACGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGCGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTCGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTACCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	89.686	100	0.897
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
covR	Streptococcus salivarius strain HSISS4	36.726	100	0.372
vicR	Streptococcus mutans UA159	35.47	100	0.372