Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BKM67_RS04695 Genome accession   NZ_CP017667
Coordinates   929202..930581 (+) Length   459 a.a.
NCBI ID   WP_112477651.1    Uniprot ID   -
Organism   Streptococcus suis strain 1081     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 924202..935581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM67_RS04665 (BKM67_04570) pstA 924502..925389 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  BKM67_RS04670 (BKM67_04575) pstB 925414..926217 (+) 804 WP_112477648.1 phosphate ABC transporter ATP-binding protein PstB -
  BKM67_RS04675 (BKM67_04580) pstB 926229..926987 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  BKM67_RS04680 (BKM67_04585) phoU 927016..927672 (+) 657 WP_112477649.1 phosphate signaling complex protein PhoU -
  BKM67_RS04685 (BKM67_04590) - 927838..928344 (+) 507 WP_024385292.1 hypothetical protein -
  BKM67_RS04690 (BKM67_04595) ciaR 928538..929209 (+) 672 WP_112477650.1 response regulator transcription factor Regulator
  BKM67_RS04695 (BKM67_04600) ciaH 929202..930581 (+) 1380 WP_112477651.1 HAMP domain-containing sensor histidine kinase Regulator
  BKM67_RS04700 (BKM67_04605) - 930682..931911 (+) 1230 WP_112477652.1 transglutaminase domain-containing protein -
  BKM67_RS04705 (BKM67_04610) rpsT 932174..932422 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  BKM67_RS04710 (BKM67_04615) coaA 932481..933401 (-) 921 WP_002935283.1 type I pantothenate kinase -
  BKM67_RS04715 (BKM67_04620) - 933510..934100 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  BKM67_RS04720 (BKM67_04625) - 934097..935374 (+) 1278 WP_024385288.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51816.42 Da        Isoelectric Point: 6.1928

>NTDB_id=201355 BKM67_RS04695 WP_112477651.1 929202..930581(+) (ciaH) [Streptococcus suis strain 1081]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDIIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKIFVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=201355 BKM67_RS04695 WP_112477651.1 929202..930581(+) (ciaH) [Streptococcus suis strain 1081]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGATCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTACGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAACAA
AAGGACTTTGTCGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGTTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGGTCTAGTTTGGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACTTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATAATCGATGTCCAACCCAACTATTTTGAT
GAAATATTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCTTGATTAAACAGTTGCTCACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACACGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTTTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae D39

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae R6

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae TIGR4

49.782

99.782

0.497
  ciaH Streptococcus mutans UA159

50.336

97.386

0.49

Multiple sequence alignment