Detailed information NTG0020090

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: SSU05_1095
• Genome accession: CP000407
• Coordinates: 1059661..1060335 (-)
• Length: 224 a.a.
• NCBI ID: ABP90061.1
• Uniprot ID: -
• Organism: Streptococcus suis 05ZYH33
• Function: repress competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1055851..1062495	1059661..1060335	within	0

Gene organization within MGE regions

Location: 1055851..1062495

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU05_1090	-	1055851..1056351 (-)	501	ABP90056.1	transposase of IS200 family	-
SSU05_1091	-	1056729..1057958 (-)	1230	ABP90057.1	Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain	-
SSU05_1092	-	1058097..1058288 (+)	192	ABP90058.1	hypothetical protein	-
SSU05_1093	-	1058210..1058317 (+)	108	ABP90059.1	hypothetical protein	-
SSU05_1094	ciaH	1058289..1059668 (-)	1380	ABP90060.1	Signal transduction histidine kinase	Regulator
SSU05_1095	ciaR	1059661..1060335 (-)	675	ABP90061.1	Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	Regulator
SSU05_1096	-	1060325..1060432 (-)	108	ABP90062.1	hypothetical protein	-
SSU05_1097	-	1060526..1060906 (-)	381	ABP90063.1	hypothetical protein	-
SSU05_1098	-	1061144..1061809 (+)	666	ABP90064.1	Transposase and inactivated derivative	-
SSU05_1099	-	1061836..1062495 (+)	660	ABP90065.1	Transposase and inactivated derivative	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25421.19 Da
• Isoelectric Point: 4.2183

>NTDB_id=20090 SSU05_1095 ABP90061.1 1059661..1060335(-) (ciaR) [Streptococcus suis 05ZYH33]
MMIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITT
AKESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLV
YFLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 675 bp

>NTDB_id=20090 SSU05_1095 ABP90061.1 1059661..1060335(-) (ciaR) [Streptococcus suis 05ZYH33]
ATGATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGA
TGTTATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAA
TGTTACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACA
GCCAAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGA
AGAATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGA
CAGTTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTT
TATTTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTAC
AATTTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCC
TGCGTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-221)

• Response regulator receiver domain (Response_reg) (5-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	99.554	0.897
ciaR	Streptococcus pneumoniae Rx1	88.341	99.554	0.879
ciaR	Streptococcus pneumoniae D39	88.341	99.554	0.879
ciaR	Streptococcus pneumoniae R6	88.341	99.554	0.879
ciaR	Streptococcus pneumoniae TIGR4	88.341	99.554	0.879
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.388
vicR	Streptococcus mutans UA159	35.47	100	0.371
covR	Streptococcus salivarius strain HSISS4	35.808	100	0.366