Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   WH25_RS08890 Genome accession   NZ_CP017295
Coordinates   1853435..1854025 (-) Length   196 a.a.
NCBI ID   WP_008809559.1    Uniprot ID   A0A0F5MH19
Organism   Streptococcus gordonii strain IE35     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1848435..1859025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS08865 (WH25_08865) - 1849083..1849847 (-) 765 WP_012130688.1 ABC transporter ATP-binding protein -
  WH25_RS08870 (WH25_08870) - 1849847..1850800 (-) 954 WP_046165252.1 branched-chain amino acid ABC transporter permease -
  WH25_RS08875 (WH25_08875) - 1850804..1851673 (-) 870 WP_008809556.1 branched-chain amino acid ABC transporter permease -
  WH25_RS08880 (WH25_08880) - 1851832..1852998 (-) 1167 WP_046165251.1 ABC transporter substrate-binding protein -
  WH25_RS08885 (WH25_08885) - 1853088..1853357 (-) 270 WP_045635066.1 YlbG family protein -
  WH25_RS08890 (WH25_08890) clpP 1853435..1854025 (-) 591 WP_008809559.1 ATP-dependent Clp protease proteolytic subunit Regulator
  WH25_RS08895 (WH25_08895) upp 1854227..1854856 (-) 630 WP_045635065.1 uracil phosphoribosyltransferase -
  WH25_RS08900 (WH25_08900) mgtA 1854954..1857614 (-) 2661 WP_046165250.1 magnesium-translocating P-type ATPase -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21376.40 Da        Isoelectric Point: 4.4829

>NTDB_id=197429 WH25_RS08890 WP_008809559.1 1853435..1854025(-) (clpP) [Streptococcus gordonii strain IE35]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGK
TVEQIHADAERDYWMSAEETLAYGFIDEIMANNNLS

Nucleotide


Download         Length: 591 bp        

>NTDB_id=197429 WH25_RS08890 WP_008809559.1 1853435..1854025(-) (clpP) [Streptococcus gordonii strain IE35]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGGGAACGCTCGTATGATATTTACTCACGCCTATTAAAAGACCGCAT
CATCATGTTGACAGGTCCGGTAGAGGATAATATGGCTAATTCAGTCATTGCTCAGCTTCTTTTCTTGGATGCACAAGACA
GTACCAAGGATATCTACCTCTATGTTAATACACCAGGTGGTTCAGTCTCAGCTGGTTTAGCGATTGTTGACACCATGAAC
TTTATTAAATCCGATGTCCAAACAATCGTTATGGGTATGGCAGCGAGCATGGGAACCATCATCGCATCAAGCGGTGCCAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATATATGATTCACCAGCCAATGGGAGGAACTGGTGGTGGTACTCAGCAAA
CGGATATGGCTATTGCTGCGGAACACTTGTTGAAGACCCGGAAAACTTTAGAGCAAATTCTTGCCGATAATTCTGGTAAA
ACAGTTGAGCAAATTCATGCTGATGCAGAACGTGATTATTGGATGAGTGCTGAAGAAACTCTTGCTTATGGATTCATTGA
TGAGATCATGGCCAACAATAATTTGAGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F5MH19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pyogenes MGAS315

92.347

100

0.923
  clpP Streptococcus pneumoniae Rx1

92.347

100

0.923
  clpP Streptococcus pneumoniae D39

92.347

100

0.923
  clpP Streptococcus pneumoniae R6

92.347

100

0.923
  clpP Streptococcus pneumoniae TIGR4

92.347

100

0.923
  clpP Streptococcus pyogenes JRS4

92.347

100

0.923
  clpP Streptococcus thermophilus LMD-9

91.282

99.49

0.908
  clpP Streptococcus thermophilus LMG 18311

91.282

99.49

0.908
  clpP Streptococcus mutans UA159

90.256

99.49

0.898
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.179

99.49

0.867
  clpP Lactococcus lactis subsp. cremoris KW2

86.667

99.49

0.862
  clpP Bacillus subtilis subsp. subtilis str. 168

57.292

97.959

0.561
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.995

98.469

0.561

Multiple sequence alignment