Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   WH25_RS04725 Genome accession   NZ_CP017295
Coordinates   973044..973745 (+) Length   233 a.a.
NCBI ID   WP_012000241.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 968044..978745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS04705 (WH25_04705) - 968387..969700 (+) 1314 WP_046165833.1 glycosyltransferase family 4 protein -
  WH25_RS04710 (WH25_04710) - 969736..970098 (+) 363 WP_046165832.1 hypothetical protein -
  WH25_RS10990 (WH25_04715) - 970432..970803 (+) 372 WP_046165831.1 hypothetical protein -
  WH25_RS04720 (WH25_04720) thrS 970895..972838 (+) 1944 WP_012000240.1 threonine--tRNA ligase -
  WH25_RS04725 (WH25_04725) micA 973044..973745 (+) 702 WP_012000241.1 response regulator YycF Regulator
  WH25_RS04730 (WH25_04730) micB 973738..975099 (+) 1362 WP_008809003.1 cell wall metabolism sensor histidine kinase VicK Regulator
  WH25_RS04735 (WH25_04735) vicX 975092..975895 (+) 804 WP_008809002.1 MBL fold metallo-hydrolase Regulator
  WH25_RS04740 (WH25_04740) - 975930..976286 (+) 357 WP_008809001.1 YbaN family protein -
  WH25_RS04745 (WH25_04745) rnc 976529..977227 (+) 699 WP_008809000.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26817.56 Da        Isoelectric Point: 4.6297

>NTDB_id=197416 WH25_RS04725 WP_012000241.1 973044..973745(+) (micA) [Streptococcus gordonii strain IE35]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQENEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=197416 WH25_RS04725 WP_012000241.1 973044..973745(+) (micA) [Streptococcus gordonii strain IE35]
ATGAAGAAAATATTAGTTGTAGATGATGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTCTTGAGATGTTTGAAGCTGAAAATCCTGATATTTTGATTTTGGATTTGA
TGTTGCCAGAGTTGGACGGGCTAGAAGTAGCACGCACCATTCGGAAGACCAGTAATGTTCCAATTATTGTCCTATCGGCT
AAAGATAGTGAGTTTGATAAAGTTATCGGCCTTGAGATCGGAGCAGACGACTATGTGACTAAGCCTTTCTCTAACCGTGA
GCTCCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCAGAATTTGCTGTAGATACCCAAGAAAATGAAAAGGGCTCAAATG
AGTTGACAGTGGGTGAATTGCAAATTTTACCTGATGCTTTTGTTGCCAAGAAACATGGTGAAGAGCTAGAATTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCTAGTCATGTTGGTCAAGTAATGACACGCGAACACCTGTTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGATGTACGCACTGTTGATGTGACGATTCGCCGTCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGTGTTGGCTATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.12

100

0.841
  vicR Streptococcus mutans UA159

80

100

0.807
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

99.142

0.446
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.5

99.571

0.373

Multiple sequence alignment