Detailed information NTG0197417

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: WH25_RS04730
• Genome accession: NZ_CP017295
• Coordinates: 973738..975099 (+)
• Length: 453 a.a.
• NCBI ID: WP_008809003.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain IE35
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 968738..980099

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WH25_RS04710 (WH25_04710)	-	969736..970098 (+)	363	WP_046165832.1	hypothetical protein	-
WH25_RS10990 (WH25_04715)	-	970432..970803 (+)	372	WP_046165831.1	hypothetical protein	-
WH25_RS04720 (WH25_04720)	thrS	970895..972838 (+)	1944	WP_012000240.1	threonine--tRNA ligase	-
WH25_RS04725 (WH25_04725)	micA	973044..973745 (+)	702	WP_012000241.1	response regulator YycF	Regulator
WH25_RS04730 (WH25_04730)	micB	973738..975099 (+)	1362	WP_008809003.1	cell wall metabolism sensor histidine kinase VicK	Regulator
WH25_RS04735 (WH25_04735)	vicX	975092..975895 (+)	804	WP_008809002.1	MBL fold metallo-hydrolase	Regulator
WH25_RS04740 (WH25_04740)	-	975930..976286 (+)	357	WP_008809001.1	YbaN family protein	-
WH25_RS04745 (WH25_04745)	rnc	976529..977227 (+)	699	WP_008809000.1	ribonuclease III	-

Sequence

Protein

• Length: 453 a.a.
• Molecular weight: 51641.69 Da
• Isoelectric Point: 4.3991

>NTDB_id=197417 WH25_RS04730 WP_008809003.1 973738..975099(+) (micB) [Streptococcus gordonii strain IE35]
MIENIRQFVFSVDFVFVLIVLGFILVVALLFLENRRDNRQLRLLNQKIKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VTRLTQENLEQETKRLTSILSYMTDGVLATNRRGQIIMINDMASKQLGVDPEEVQNTSILDLLDIADEYDLRDLITKMPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPEFVKVSLTETNRMMRMVSDLLSLSRIDNDSSHLDVELTNFTAFITFILNRFDKIKSQDETKKYEIVRDYPITPIW
VEIDTDKMTQVIDNIMNNAIKYSPDGGKITVGMKTTEDQLIISISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHHGFIWAKSEYEVGSTFTIVLPYDKDAVLDDGWESEEVESKDD

Nucleotide

• Length: 1362 bp

>NTDB_id=197417 WH25_RS04730 WP_008809003.1 973738..975099(+) (micB) [Streptococcus gordonii strain IE35]
ATGATTGAAAATATTAGACAATTTGTGTTTTCTGTAGATTTTGTTTTTGTTTTAATTGTTTTAGGTTTTATTTTGGTTGT
TGCCCTGCTCTTTTTAGAGAATCGAAGGGATAATCGCCAACTTCGTCTGCTCAATCAAAAGATCAAAGATTTAATCGCAG
GAGACTATTCCGAGGTTCTGGATATGCAGGGCAGTCCAGAAATTACGGATATGACCAATAGTATAAATGATTTGTCTGAG
GTAACTAGATTAACACAAGAAAATCTGGAGCAAGAAACCAAACGTTTGACTAGTATTTTGTCCTACATGACGGATGGGGT
TTTGGCAACCAACCGTAGGGGTCAGATTATCATGATTAATGATATGGCTTCTAAGCAATTAGGTGTTGATCCAGAGGAAG
TCCAAAATACAAGTATTTTAGACTTGTTAGATATTGCGGATGAATATGATCTGCGGGATTTAATTACCAAGATGCCGGAA
TTGACGATTGATTCACAGGATGAAAATGGAGAATATCTAAGTCTGCGTGTTCGTTTTGCCTTGGTTCGTAGGGAATCTGG
TTTTATCTCTGGTTTGGTAGCTGTTTTGCACGATACGACAGAACAGGAAAAAGAGGAACGGGAGCGTCGGCTTTTTGTAT
CAAACGTAAGTCATGAGCTCCGGACCCCTTTAACAAGTGTTAAGTCTTACCTAGAAGCTTTGGACGAGGGCGCTCTTTCT
GAGCCAGTTGCTCCTGAATTTGTTAAAGTTTCTCTTACTGAAACGAACCGAATGATGCGGATGGTTTCTGATTTGCTTAG
CTTATCAAGGATTGATAATGATAGTAGTCATTTGGATGTAGAATTAACTAATTTTACAGCTTTTATCACTTTTATTTTGA
ATCGTTTTGATAAGATTAAAAGTCAGGATGAAACCAAAAAATATGAGATTGTACGAGATTATCCAATCACACCTATTTGG
GTTGAAATTGATACTGATAAAATGACGCAGGTCATTGATAATATCATGAATAATGCTATCAAGTATTCTCCAGATGGTGG
AAAGATTACCGTAGGGATGAAAACGACGGAAGATCAGCTGATTATTTCAATTTCTGATGAAGGATTGGGAATTCCCAAAA
AAGACTTGCCTAAGATCTTTGACCGTTTTTATCGAGTGGATAAGGCTCGAAGCCGTGCGCAAGGTGGAACGGGCTTAGGA
CTTGCGATTGCAAAAGAAATCATCAAGCAGCACCATGGCTTTATCTGGGCCAAGAGTGAGTATGAAGTCGGATCAACTTT
TACAATTGTCCTGCCGTATGATAAGGATGCTGTTTTGGATGATGGCTGGGAAAGTGAAGAAGTAGAAAGTAAAGATGACT
AA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (96-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	80.822	96.689	0.781
vicK	Streptococcus mutans UA159	70.316	90.728	0.638