Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   WH25_RS00420 Genome accession   NZ_CP017295
Coordinates   94009..96162 (-) Length   717 a.a.
NCBI ID   WP_046164565.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 89009..101162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS00405 (WH25_00405) purD 89369..90628 (-) 1260 WP_046164562.1 phosphoribosylamine--glycine ligase -
  WH25_RS00410 (WH25_00410) lytF 90873..92522 (+) 1650 WP_046164563.1 GBS Bsp-like repeat-containing protein Regulator
  WH25_RS00415 (WH25_00415) comB 92641..93999 (-) 1359 WP_046164564.1 competence pheromone export protein ComB Regulator
  WH25_RS00420 (WH25_00420) comA 94009..96162 (-) 2154 WP_046164565.1 peptide cleavage/export ABC transporter ComA Regulator
  WH25_RS00425 (WH25_00425) rpsD 96616..97227 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  WH25_RS00430 (WH25_00430) - 97494..98216 (-) 723 WP_046164566.1 ABC transporter ATP-binding protein -
  WH25_RS00435 (WH25_00435) - 98216..99217 (-) 1002 WP_155759326.1 ABC transporter substrate-binding protein -
  WH25_RS00440 (WH25_00440) - 99258..100010 (-) 753 WP_046164568.1 ABC transporter permease -
  WH25_RS00445 (WH25_00445) - 99973..100263 (-) 291 WP_046164586.1 thiamine-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80605.64 Da        Isoelectric Point: 7.0505

>NTDB_id=197393 WH25_RS00420 WP_046164565.1 94009..96162(-) (comA) [Streptococcus gordonii strain IE35]
MKFRKRHYRAQVDTRDCGVAALAMVFGYYGSYFSLATLREKAKTTNDGTTALGLVKVAEGLNFETRAFKADMGIFDLEDV
SYPFIVHVLKEGKLLHYYVVTGQDKHTIHIADPDPQVKMTKISRERFEQEWTGITIFLAPSPAYKPSQEKKNGLLDFIPL
LIKQKGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEIVSRFTDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYAL
IIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVTYLKKSFAYGRSESLQKVLKAAARL
ILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVKSEFEEEKLIKDLSHL
QADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYGPNQGDICLGGVNLNQLDKQALRQYI
NYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIIDNLMALDKTIIFIAHRLTIAERSEQVVVLDQGRIVESGSHKELIEKEGFYHHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=197393 WH25_RS00420 WP_046164565.1 94009..96162(-) (comA) [Streptococcus gordonii strain IE35]
ATGAAATTTAGGAAACGGCATTACAGAGCACAAGTTGATACTAGGGATTGCGGAGTGGCAGCTCTGGCTATGGTTTTTGG
TTATTATGGATCGTATTTTTCCTTGGCTACACTGCGAGAAAAGGCAAAAACGACTAATGATGGCACAACAGCTTTGGGTT
TGGTAAAAGTTGCTGAGGGCTTAAATTTTGAGACAAGGGCTTTTAAAGCTGATATGGGAATCTTTGATCTGGAAGATGTA
TCTTATCCTTTCATCGTTCATGTACTTAAGGAAGGGAAGCTCCTGCATTATTATGTTGTGACGGGCCAAGATAAACACAC
GATTCATATTGCAGACCCAGATCCTCAAGTTAAGATGACAAAGATTTCGCGAGAGCGTTTCGAACAGGAGTGGACAGGGA
TTACCATTTTCCTAGCTCCTAGTCCAGCCTATAAACCTAGTCAGGAAAAGAAAAATGGACTTTTAGACTTCATTCCCTTA
TTGATTAAGCAGAAGGGATTGATTGCTAATATTGTACTTGCAACTTTGCTGGTAACGTTGATCAATATTGTTGGATCCTA
CTACCTTCAATCGATTATTGATACTTATGTGCCTGATCATATGAAAACGACGCTGGGTATGATTTCTATCGGCTTGATTA
TTGTCTACATTTTGCAGCAATTCTTGTCTTATGCCCAAGAATATTTACTCTTGGTTTTGGGGCAGCGTCTATCAATTGAT
GTGATTTTATCTTATATCAAGCACGTTTTTCAGCTACCTATGTCATTTTTCGCGACAAGGCGGACAGGGGAAATCGTCTC
TCGTTTTACAGACGCCAATCGGATTATTGATGCCTTGGCCAGTACAATCTTGTCTATTTTCTTGGATGTGTCAATTGTGT
CGATCATTGCGATTGTTCTTTTTTCACAAAATAGCAGTCTTTTCTTTTTGACCTTGCTAGGAATCCCAGTTTACGCTCTC
ATTATTTTTCTTTTTATGAAACCTTTTGAAAAGATGAATCATGAGACGATGGAAGCAAATAGTCTGTTGTCGTCTTCCAT
CATTGAAGATATCAATGGGATTGAAACGATTAAGTCTTTGACCAGCGAAAAACAACGTTATCAGAAGATTGACAAGGAAT
TTGTGACTTATCTGAAAAAGTCTTTTGCTTACGGGCGTTCTGAGAGCCTACAAAAAGTCTTGAAAGCAGCAGCTCGTTTG
ATTTTAAACGTCTTGATTTTATGGCTAGGAGCTACACTTGTCATGGATCAAAAAATCAGCCTTGGTCAGCTCATTACTTA
TAACACACTTCTAGTCTACTTTACTAATCCTTTAGAAAATATTATCAATCTGCAAACGAAGTTACAGTCTGCACGAGTGG
CTAATGAGCGCCTCAATGAGGTTTATTTGGTGAAGTCTGAATTTGAAGAAGAGAAGCTTATCAAGGACTTGAGCCACTTG
CAGGCTGACATCGATTTTCGTGGAGTCAGCTATAAATATGGCTATGGGGCCAATGTATTGTCAGAAATTGACTTGCATAT
TCCTGCTGGAAGTAAGACAAGCTTTGTTGGTGTATCAGGATCGGGAAAAACAACCTTGGCCAAGATGATGGTGCATTTTT
ATGGTCCGAATCAAGGGGATATTTGTCTGGGAGGAGTCAATCTCAATCAGCTGGATAAGCAGGCGCTGCGCCAATATATC
AACTATCTTCCCCAGCAACCGTATGTTTTTAATGGAACTATTTTGGAAAATTTACTCTTAGGTGCGCGTGAAGGCACGAC
TCAAGAAGATATTCTGCGGGCGGTAGAGCTGGCGGAAATTAGGTCGGATATTGAGCGGATGCCCCTCAATTATCAGACAG
AGTTGTCTGCAGATGGTGCAGGAATTTCGGGTGGTCAACGTCAGCGTATTGCTCTAGCGAGGGCTCTCTTGACAGATGCG
CCAGTGCTTATCTTAGATGAAGCAACAAGCAGTCTGGATATTCTAACGGAGAAGCGGATCATTGATAATTTGATGGCGCT
TGATAAGACGATTATTTTTATCGCGCATCGTTTGACTATTGCGGAACGTTCGGAGCAGGTGGTCGTTTTGGATCAAGGTA
GGATTGTTGAGAGTGGAAGTCATAAGGAGCTGATCGAAAAAGAAGGCTTTTACCACCATTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

98.047

100

0.98
  comA Streptococcus mitis NCTC 12261

81.311

100

0.813
  comA Streptococcus pneumoniae Rx1

81.172

100

0.812
  comA Streptococcus pneumoniae D39

81.172

100

0.812
  comA Streptococcus pneumoniae R6

81.172

100

0.812
  comA Streptococcus mitis SK321

80.893

100

0.809
  comA Streptococcus pneumoniae TIGR4

80.753

100

0.808
  comA/nlmT Streptococcus mutans UA159

65.132

100

0.651

Multiple sequence alignment