Detailed information NTG0197392

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: WH25_RS00415
• Genome accession: NZ_CP017295
• Coordinates: 92641..93999 (-)
• Length: 452 a.a.
• NCBI ID: WP_046164564.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain IE35
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 87641..98999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WH25_RS00400 (WH25_00400)	-	88116..89309 (-)	1194	WP_046164561.1	ATP-grasp domain-containing protein	-
WH25_RS00405 (WH25_00405)	purD	89369..90628 (-)	1260	WP_046164562.1	phosphoribosylamine--glycine ligase	-
WH25_RS00410 (WH25_00410)	lytF	90873..92522 (+)	1650	WP_046164563.1	GBS Bsp-like repeat-containing protein	Regulator
WH25_RS00415 (WH25_00415)	comB	92641..93999 (-)	1359	WP_046164564.1	competence pheromone export protein ComB	Regulator
WH25_RS00420 (WH25_00420)	comA	94009..96162 (-)	2154	WP_046164565.1	peptide cleavage/export ABC transporter ComA	Regulator
WH25_RS00425 (WH25_00425)	rpsD	96616..97227 (-)	612	WP_008810013.1	30S ribosomal protein S4	-
WH25_RS00430 (WH25_00430)	-	97494..98216 (-)	723	WP_046164566.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 452 a.a.
• Molecular weight: 49788.03 Da
• Isoelectric Point: 6.2674

>NTDB_id=197392 WH25_RS00415 WP_046164564.1 92641..93999(-) (comB) [Streptococcus gordonii strain IE35]
MNEQFLESAEFYQKRYHNFASCLIVPSLFLLVFLVGFSMLAKKEITISSRASVEASRVLAQIQSTSNQAIIANHLAENKE
VKKGDLLIQYAVEGEGAQEQKFSSQLDLLKDQKGKLETLRSSLESGRNQFTEPDSYGYEQSFKDYQNQVASMTSSVNQQN
ATIASQNAAASQSQAELGGVISDVDSKLNDHRNLKNAIQSGVGIDASHPLHSLYQSYRDQLSLAEDKATAQSQIVAQLDG
QISQLEATAATYRVQYAGAGAQQAYASNLSSQLASLKAQYLVKVGQELTTLTQQILEAESNLKLQETVSKRGQILAEMDG
LLHLNPEVQGSTLVAEGTALAQIYPKITSERKIKIVTYVSSKDVSTIKNGDKVRFITADDANKQMILTSQISSIDANATQ
TKQGNFFKVECEMAVSKDQAKKLRYGLEGKFVMVTGEKTYFSYYMEKFFNLG

Nucleotide

• Length: 1359 bp

>NTDB_id=197392 WH25_RS00415 WP_046164564.1 92641..93999(-) (comB) [Streptococcus gordonii strain IE35]
ATGAATGAACAATTTTTAGAAAGTGCAGAGTTTTATCAGAAACGTTATCATAATTTTGCTAGTTGTCTAATTGTGCCAAG
TCTTTTTTTACTAGTATTTCTAGTTGGTTTTTCTATGCTGGCTAAAAAGGAAATTACAATTTCTAGCCGTGCTTCTGTAG
AAGCTAGCCGAGTGCTAGCTCAGATTCAGTCGACTAGTAACCAGGCTATCATTGCGAATCATTTGGCAGAAAACAAGGAG
GTCAAAAAAGGGGACCTGCTAATCCAGTATGCAGTAGAAGGAGAGGGAGCTCAGGAACAGAAGTTTTCCAGCCAGCTTGA
CTTACTCAAAGATCAAAAGGGCAAACTAGAAACTTTGCGTTCCAGTTTAGAAAGCGGGCGTAATCAATTCACTGAGCCAG
ATAGTTATGGCTACGAACAAAGCTTTAAAGACTACCAGAATCAAGTAGCGAGTATGACTAGTTCTGTGAATCAGCAAAAT
GCTACGATTGCTTCCCAAAATGCAGCGGCCAGTCAGTCTCAGGCGGAACTGGGCGGTGTTATCAGTGATGTGGATAGCAA
ACTAAATGACCATCGAAACTTGAAAAATGCCATTCAAAGTGGGGTAGGTATAGATGCATCGCATCCTCTTCACTCCCTGT
ACCAGTCCTATCGTGATCAGTTGAGCCTGGCGGAGGATAAGGCAACAGCTCAAAGTCAGATTGTAGCTCAATTAGATGGG
CAAATCTCTCAATTAGAAGCAACAGCTGCGACTTATCGTGTCCAATATGCTGGTGCAGGCGCTCAACAAGCCTATGCTAG
CAATTTATCCAGTCAGTTGGCTTCACTGAAAGCCCAGTATCTGGTCAAGGTAGGACAAGAATTGACCACTCTGACTCAGC
AAATCTTGGAAGCCGAGAGCAATCTTAAACTTCAAGAAACAGTCTCTAAGCGAGGTCAGATTTTGGCTGAAATGGATGGC
TTGCTTCACTTAAATCCAGAAGTACAAGGATCTACTCTGGTGGCAGAAGGAACTGCTTTGGCTCAGATTTATCCTAAAAT
CACCAGTGAACGAAAAATCAAAATTGTCACATATGTCTCTTCCAAGGATGTATCTACTATTAAAAATGGAGACAAGGTGC
GCTTTATCACTGCTGATGATGCTAACAAACAAATGATTTTGACATCCCAAATTTCCAGTATTGATGCTAATGCTACCCAA
ACCAAACAGGGAAATTTCTTTAAAGTAGAATGCGAAATGGCTGTTAGTAAAGATCAAGCTAAGAAGCTCCGCTATGGCTT
GGAAGGTAAATTTGTCATGGTAACTGGGGAAAAGACTTATTTCAGCTATTATATGGAGAAGTTTTTTAATCTTGGTTGA

Domains

Predicted by InterproScan.

• HlyD family secretion protein (HlyD_3) (314-426)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus gordonii str. Challis substr. CH1	98.894	100	0.989
comB	Streptococcus pneumoniae Rx1	55.778	99.558	0.555
comB	Streptococcus pneumoniae D39	55.778	99.558	0.555
comB	Streptococcus pneumoniae R6	55.778	99.558	0.555
comB	Streptococcus mitis NCTC 12261	55.556	99.558	0.553
comB	Streptococcus pneumoniae TIGR4	55.333	99.558	0.551
comB	Streptococcus mitis SK321	54.889	99.558	0.546