Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CDH88_RS05170 Genome accession   NZ_CP021840
Coordinates   983986..984618 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain EC974     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 978986..989618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CDH88_RS05140 (CDH88_05135) yheS 979155..981068 (+) 1914 WP_021578014.1 ABC transporter ATP-binding protein -
  CDH88_RS05145 (CDH88_05140) yheT 981068..982090 (+) 1023 WP_021578015.1 hydrolase -
  CDH88_RS05150 (CDH88_05145) yheU 982084..982302 (+) 219 WP_000907085.1 YheU family protein -
  CDH88_RS05155 (CDH88_05150) prkB 982356..983225 (+) 870 WP_001274680.1 phosphoribulokinase -
  CDH88_RS05160 (CDH88_05155) yhfA 983280..983684 (-) 405 WP_001148908.1 OsmC family protein -
  CDH88_RS05170 (CDH88_05165) crp 983986..984618 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CDH88_RS05175 (CDH88_05170) yhfK 984669..986759 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CDH88_RS05180 (CDH88_05175) argD 986826..988046 (-) 1221 WP_021578016.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CDH88_RS05185 (CDH88_05180) pabA 988132..988695 (-) 564 WP_000601856.1 aminodeoxychorismate synthase component 2 -
  CDH88_RS05190 (CDH88_05185) fic 988727..989329 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CDH88_RS05195 (CDH88_05190) yhfG 989319..989486 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=196579 CDH88_RS05170 WP_000242755.1 983986..984618(+) (crp) [Escherichia coli strain EC974]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=196579 CDH88_RS05170 WP_000242755.1 983986..984618(+) (crp) [Escherichia coli strain EC974]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment