Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   CCZ24_RS06060 Genome accession   NZ_CP021773
Coordinates   1214114..1214767 (-) Length   217 a.a.
NCBI ID   WP_000461741.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain B105     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1209114..1219767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCZ24_RS06045 (CCZ24_05970) - 1210003..1210947 (-) 945 WP_000200834.1 LacI family DNA-binding transcriptional regulator -
  CCZ24_RS06050 (CCZ24_05975) - 1210958..1211767 (-) 810 WP_000153219.1 Cof-type HAD-IIB family hydrolase -
  CCZ24_RS06055 (CCZ24_05980) comEC/celB 1211893..1214130 (-) 2238 WP_000902956.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CCZ24_RS06060 (CCZ24_05985) comEA/celA/cilE 1214114..1214767 (-) 654 WP_000461741.1 helix-hairpin-helix domain-containing protein Machinery gene
  CCZ24_RS06065 (CCZ24_05990) - 1214867..1215607 (-) 741 WP_000500222.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  CCZ24_RS06070 (CCZ24_05995) - 1215742..1216506 (+) 765 WP_000567428.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  CCZ24_RS06075 (CCZ24_06000) - 1216499..1216765 (+) 267 WP_000598735.1 GIY-YIG nuclease family protein -
  CCZ24_RS06080 (CCZ24_06005) - 1216948..1218534 (-) 1587 WP_000673086.1 DEAD/DEAH box helicase -
  CCZ24_RS06085 (CCZ24_06010) - 1218769..1219617 (-) 849 WP_000735508.1 MetQ/NlpA family ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23714.05 Da        Isoelectric Point: 9.2366

>NTDB_id=196221 CCZ24_RS06060 WP_000461741.1 1214114..1214767(-) (comEA/celA/cilE) [Streptococcus agalactiae strain B105]
MFEIVLEKIKSHKWETTGIIVGLLLFGILGLNHFGTHHKEDDLNINLEKKVSTITEKKVPMISHVKDKVSNQVTVDVKGA
VNHPGVYSLPSQSRVTDAIKRAGGLSNLADSKSVNLAQKLQDETVIYVAQKGEKITVVEEEKANNIATQGNSKGKINLNK
ADLSSLQTISGVGAKRAQDILDYRDSQGGFKTIDDLKNVSGIGEKTLEKLRQDVTLD

Nucleotide


Download         Length: 654 bp        

>NTDB_id=196221 CCZ24_RS06060 WP_000461741.1 1214114..1214767(-) (comEA/celA/cilE) [Streptococcus agalactiae strain B105]
ATGTTTGAAATAGTATTGGAAAAAATTAAATCGCATAAATGGGAGACAACAGGAATTATTGTAGGACTCTTATTGTTTGG
AATTTTGGGTTTAAATCATTTTGGCACTCATCATAAAGAAGACGATTTAAATATCAATTTAGAGAAAAAAGTATCAACTA
TAACAGAAAAAAAGGTACCAATGATTAGTCACGTCAAAGATAAAGTATCTAATCAAGTAACGGTTGACGTAAAAGGGGCA
GTCAATCATCCAGGTGTTTATAGTTTGCCTTCTCAAAGTCGTGTAACAGATGCGATTAAGCGTGCAGGTGGACTAAGCAA
TCTCGCTGATAGTAAATCCGTTAATCTAGCACAGAAATTACAAGATGAGACGGTTATCTATGTTGCTCAAAAAGGTGAAA
AAATAACTGTTGTGGAAGAGGAGAAAGCAAATAATATTGCTACTCAGGGAAATAGTAAGGGGAAAATTAATCTTAATAAA
GCAGATTTATCAAGTCTTCAGACCATATCAGGCGTTGGAGCTAAAAGAGCTCAAGATATTTTAGATTATCGTGATAGTCA
AGGTGGTTTTAAAACTATTGATGACCTCAAAAATGTATCAGGTATTGGTGAGAAAACACTAGAAAAATTACGTCAAGATG
TTACACTTGACTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(153-215)

SLBB domain (SLBB)

(75-128)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

44.595

100

0.456
  comEA/celA/cilE Streptococcus mitis SK321

44.144

100

0.452
  comEA/celA/cilE Streptococcus pneumoniae Rx1

43.694

100

0.447
  comEA/celA/cilE Streptococcus pneumoniae D39

43.694

100

0.447
  comEA/celA/cilE Streptococcus pneumoniae R6

43.694

100

0.447
  comEA/celA/cilE Streptococcus mitis NCTC 12261

43.243

100

0.442
  comEA Lactococcus lactis subsp. cremoris KW2

38.565

100

0.396
  comEA Streptococcus thermophilus LMD-9

56

69.124

0.387

Multiple sequence alignment