Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   A7J08_RS03290 Genome accession   NZ_CP017088
Coordinates   642300..643004 (+) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain SRD478     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 637300..648004
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS03265 (A7J08_03130) - 638198..639061 (+) 864 WP_053866999.1 hypothetical protein -
  A7J08_RS03270 (A7J08_03135) - 639107..639766 (-) 660 WP_024384909.1 amino acid ABC transporter permease -
  A7J08_RS03275 (A7J08_03140) - 639781..640479 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  A7J08_RS03280 (A7J08_03145) - 640494..641333 (-) 840 WP_044758261.1 transporter substrate-binding domain-containing protein -
  A7J08_RS03285 (A7J08_03150) - 641344..642105 (-) 762 WP_053867000.1 amino acid ABC transporter ATP-binding protein -
  A7J08_RS03290 (A7J08_03155) micA 642300..643004 (+) 705 WP_002935840.1 response regulator YycF Regulator
  A7J08_RS03295 (A7J08_03160) micB 642997..644346 (+) 1350 WP_053867001.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A7J08_RS03300 (A7J08_03165) vicX 644353..645156 (+) 804 WP_029172537.1 MBL fold metallo-hydrolase Regulator
  A7J08_RS10560 - 645414..646250 (+) 837 WP_235443465.1 ATP-binding cassette domain-containing protein -
  A7J08_RS10565 (A7J08_03175) - 646290..646799 (+) 510 WP_235443466.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=195395 A7J08_RS03290 WP_002935840.1 642300..643004(+) (micA) [Streptococcus suis strain SRD478]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=195395 A7J08_RS03290 WP_002935840.1 642300..643004(+) (micA) [Streptococcus suis strain SRD478]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment