Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   A7J08_RS03295 Genome accession   NZ_CP017088
Coordinates   642997..644346 (+) Length   449 a.a.
NCBI ID   WP_053867001.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 637997..649346
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS03265 (A7J08_03130) - 638198..639061 (+) 864 WP_053866999.1 hypothetical protein -
  A7J08_RS03270 (A7J08_03135) - 639107..639766 (-) 660 WP_024384909.1 amino acid ABC transporter permease -
  A7J08_RS03275 (A7J08_03140) - 639781..640479 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  A7J08_RS03280 (A7J08_03145) - 640494..641333 (-) 840 WP_044758261.1 transporter substrate-binding domain-containing protein -
  A7J08_RS03285 (A7J08_03150) - 641344..642105 (-) 762 WP_053867000.1 amino acid ABC transporter ATP-binding protein -
  A7J08_RS03290 (A7J08_03155) micA 642300..643004 (+) 705 WP_002935840.1 response regulator YycF Regulator
  A7J08_RS03295 (A7J08_03160) micB 642997..644346 (+) 1350 WP_053867001.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A7J08_RS03300 (A7J08_03165) vicX 644353..645156 (+) 804 WP_029172537.1 MBL fold metallo-hydrolase Regulator
  A7J08_RS10560 - 645414..646250 (+) 837 WP_235443465.1 ATP-binding cassette domain-containing protein -
  A7J08_RS10565 (A7J08_03175) - 646290..646799 (+) 510 WP_235443466.1 ATP-binding cassette domain-containing protein -
  A7J08_RS03310 (A7J08_03180) pbp2b 646891..648966 (+) 2076 WP_053867002.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51047.14 Da        Isoelectric Point: 4.5202

>NTDB_id=195396 A7J08_RS03295 WP_053867001.1 642997..644346(+) (micB) [Streptococcus suis strain SRD478]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHINENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=195396 A7J08_RS03295 WP_053867001.1 642997..644346(+) (micB) [Streptococcus suis strain SRD478]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTGGACATGAGGGGAAGTCCTGAAATCACAGACATGGCTAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACCCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATTCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCATCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACATCAATGAAAATGAAGAATTTCTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
CCTGATTTCTGGCTTGGTAGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTATTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment