Detailed information NTG0194957

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: BGL51_RS01510
• Genome accession: NZ_CP017064
• Coordinates: 276376..277275 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain ST3
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 271376..282275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BGL51_RS01490 (BGL51_01535)	trkA	272512..273861 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
BGL51_RS01495 (BGL51_01540)	-	274120..274659 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
BGL51_RS01500 (BGL51_01545)	-	274971..275528 (+)	558	WP_002949523.1	ECF transporter S component	-
BGL51_RS01505 (BGL51_01550)	-	275531..276181 (+)	651	WP_095559229.1	phosphatase PAP2 family protein	-
BGL51_RS01510 (BGL51_01555)	comR	276376..277275 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
BGL51_RS01515 (BGL51_01565)	-	277513..278691 (+)	1179	Protein_245	ABC transporter transmembrane domain-containing protein	-
BGL51_RS10370 (BGL51_01575)	comA	278713..278922 (+)	210	WP_002946147.1	hypothetical protein	Regulator
BGL51_RS01535 (BGL51_01580)	-	278977..279545 (+)	569	Protein_247	ATP-binding cassette domain-containing protein	-
BGL51_RS01540 (BGL51_01585)	-	279672..279983 (+)	312	WP_095559231.1	DUF805 domain-containing protein	-
BGL51_RS10375	-	279951..280235 (-)	285	WP_232085805.1	hypothetical protein	-
BGL51_RS10380 (BGL51_01590)	-	280475..281371 (-)	897	WP_224102957.1	urease cluster protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=194957 BGL51_RS01510 WP_014607953.1 276376..277275(+) (comR) [Streptococcus thermophilus strain ST3]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=194957 BGL51_RS01510 WP_014607953.1 276376..277275(+) (comR) [Streptococcus thermophilus strain ST3]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAATCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418