Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   CCX85_RS04915 Genome accession   NZ_CP021640
Coordinates   974176..974364 (-) Length   62 a.a.
NCBI ID   WP_011054546.1    Uniprot ID   A0A0H2UUN1
Organism   Streptococcus pyogenes strain JS12     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 969176..979364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCX85_RS04890 (CCX85_04895) - 970980..971351 (+) 372 WP_002989617.1 GntR family transcriptional regulator -
  CCX85_RS04895 (CCX85_04900) - 971351..972049 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  CCX85_RS04900 (CCX85_04905) - 972059..972844 (+) 786 WP_002984433.1 hypothetical protein -
  CCX85_RS04905 (CCX85_04910) - 972971..973585 (-) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  CCX85_RS04915 (CCX85_04920) prx 974176..974364 (-) 189 WP_011054546.1 hypothetical protein Regulator
  CCX85_RS04920 (CCX85_04925) spel 974479..975267 (-) 789 WP_021340779.1 streptococcal pyrogenic exotoxin SpeL -
  CCX85_RS04925 (CCX85_04930) spem 975549..976262 (-) 714 WP_014635497.1 streptococcal pyrogenic exotoxin SpeM -
  CCX85_RS04930 (CCX85_04935) - 976565..977431 (-) 867 WP_011054729.1 DUF334 domain-containing protein -
  CCX85_RS04935 (CCX85_04940) - 977419..977943 (-) 525 WP_011017840.1 Panacea domain-containing protein -
  CCX85_RS04940 (CCX85_04945) - 978099..978740 (-) 642 Protein_913 CHAP domain-containing protein -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7226.17 Da        Isoelectric Point: 3.9947

>NTDB_id=194448 CCX85_RS04915 WP_011054546.1 974176..974364(-) (prx) [Streptococcus pyogenes strain JS12]
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=194448 CCX85_RS04915 WP_011054546.1 974176..974364(-) (prx) [Streptococcus pyogenes strain JS12]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGATGACGGATATATCGTAGGAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGGAAGCGAGAAATGGAGAAGTTGTGACAGAGGAGAAGGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UUN1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS315

84.746

95.161

0.806

  prx Streptococcus pyogenes MGAS8232

84.483

93.548

0.79

  prx Streptococcus pyogenes MGAS315

82.759

93.548

0.774

  prx Streptococcus pyogenes MGAS315

77.966

95.161

0.742

  prx Streptococcus pyogenes MGAS315

87.805

66.129

0.581

  prx Streptococcus pyogenes MGAS315

76.19

67.742

0.516


Multiple sequence alignment