Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   BFM96_RS07435 Genome accession   NZ_CP016953
Coordinates   1592080..1592781 (+) Length   233 a.a.
NCBI ID   WP_068992434.1    Uniprot ID   A0A917A5E2
Organism   Streptococcus himalayensis strain HTS2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1587080..1597781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS07410 pstB 1587125..1587883 (+) 759 WP_068992423.1 phosphate ABC transporter ATP-binding protein PstB -
  BFM96_RS07415 phoU 1587894..1588547 (+) 654 WP_068994254.1 phosphate signaling complex protein PhoU -
  BFM96_RS07420 - 1588717..1590261 (+) 1545 WP_068992426.1 ClC family H(+)/Cl(-) exchange transporter -
  BFM96_RS07425 guaC 1590421..1591404 (+) 984 WP_068992429.1 GMP reductase -
  BFM96_RS07430 - 1591520..1591924 (-) 405 WP_068992431.1 DUF6556 family protein -
  BFM96_RS07435 micA 1592080..1592781 (+) 702 WP_068992434.1 response regulator YycF Regulator
  BFM96_RS07440 micB 1592774..1594126 (+) 1353 WP_068992437.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BFM96_RS07445 vicX 1594127..1594930 (+) 804 WP_068992441.1 MBL fold metallo-hydrolase Regulator
  BFM96_RS11545 - 1595358..1595594 (+) 237 Protein_1436 IS630 family transposase -
  BFM96_RS07450 rpiA 1595828..1596511 (+) 684 WP_068992444.1 ribose-5-phosphate isomerase RpiA -
  BFM96_RS07455 - 1596514..1597725 (+) 1212 WP_068992446.1 phosphopentomutase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26785.91 Da        Isoelectric Point: 4.9953

>NTDB_id=194051 BFM96_RS07435 WP_068992434.1 1592080..1592781(+) (micA) [Streptococcus himalayensis strain HTS2]
MKKILVVDDEKPISDIIKFNMVKEGYEVLTAFNGREALEMFEAERPDILILDLMLPEIDGLEVAKTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRAELAPENQDAQAEQTEITIGKLQILKDAFVAKKLGKELELTH
REFELLLHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDVPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=194051 BFM96_RS07435 WP_068992434.1 1592080..1592781(+) (micA) [Streptococcus himalayensis strain HTS2]
ATGAAAAAAATATTAGTTGTAGATGATGAAAAGCCCATTTCAGATATTATCAAGTTTAACATGGTCAAGGAAGGCTATGA
AGTACTGACGGCTTTCAATGGTCGTGAGGCCCTGGAGATGTTTGAGGCAGAGCGTCCTGACATTTTGATTTTGGACTTGA
TGTTGCCAGAGATTGATGGATTAGAGGTCGCAAAGACCATCCGCAAAACCAGCAATGTTCCGATTATTGTCCTATCTGCC
AAGGATAGTGAGTTTGACAAGGTCATCGGACTTGAGATTGGGGCGGATGATTATGTGACCAAACCTTTTTCCAATCGGGA
GTTGCAAGCGCGTGTCAAGGCTATTTTGCGTCGTGCGGAGCTGGCCCCTGAAAATCAAGACGCCCAAGCTGAGCAGACCG
AGATTACCATCGGCAAGCTTCAAATTCTAAAAGATGCTTTTGTTGCGAAAAAACTAGGCAAGGAATTGGAATTAACTCAT
CGTGAATTTGAGCTCTTGCTCCACTTAGCTACGCATGTAGGTCAAGTGATGACACGAGAGCATTTGCTCGAGACTGTCTG
GGGCTATGATTATTTTGGAGATGTGCGGACGGTGGATGTGACCATTCGTCGCTTGAGAGAAAAAATTGAAGACGTCCCAA
GCCGACCAGAATATATCTTAACGCGTCGTGGTGTGGGCTATTACATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

78.571

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.288

98.283

0.455
  covR Streptococcus salivarius strain HSISS4

43.913

98.712

0.433
  scnR Streptococcus mutans UA159

37.391

98.712

0.369

Multiple sequence alignment