Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   BFM96_RS07440 Genome accession   NZ_CP016953
Coordinates   1592774..1594126 (+) Length   450 a.a.
NCBI ID   WP_068992437.1    Uniprot ID   A0A917A5G9
Organism   Streptococcus himalayensis strain HTS2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1587774..1599126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS07415 phoU 1587894..1588547 (+) 654 WP_068994254.1 phosphate signaling complex protein PhoU -
  BFM96_RS07420 - 1588717..1590261 (+) 1545 WP_068992426.1 ClC family H(+)/Cl(-) exchange transporter -
  BFM96_RS07425 guaC 1590421..1591404 (+) 984 WP_068992429.1 GMP reductase -
  BFM96_RS07430 - 1591520..1591924 (-) 405 WP_068992431.1 DUF6556 family protein -
  BFM96_RS07435 micA 1592080..1592781 (+) 702 WP_068992434.1 response regulator YycF Regulator
  BFM96_RS07440 micB 1592774..1594126 (+) 1353 WP_068992437.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BFM96_RS07445 vicX 1594127..1594930 (+) 804 WP_068992441.1 MBL fold metallo-hydrolase Regulator
  BFM96_RS11545 - 1595358..1595594 (+) 237 Protein_1436 IS630 family transposase -
  BFM96_RS07450 rpiA 1595828..1596511 (+) 684 WP_068992444.1 ribose-5-phosphate isomerase RpiA -
  BFM96_RS07455 - 1596514..1597725 (+) 1212 WP_068992446.1 phosphopentomutase -
  BFM96_RS07460 - 1597727..1598257 (+) 531 WP_068992449.1 ClbS/DfsB family four-helix bundle protein -
  BFM96_RS07465 - 1598267..1598827 (+) 561 WP_068992452.1 GTP pyrophosphokinase -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51227.42 Da        Isoelectric Point: 4.5351

>NTDB_id=194052 BFM96_RS07440 WP_068992437.1 1592774..1594126(+) (micB) [Streptococcus himalayensis strain HTS2]
MIETIKSFIVSKDFIFVLLILGFVLVIALLTLENRRDNLRIRELNQKVKDLIAGDYSEVLDMQGGPEITDITNSLNDLSE
VIRLTHENLEQESKRLNSILSYMTDGVLATNRRGKIIMINDMAARQLGVKKEEAENLNILQLLGIEEEYELRDLITKVPD
VTIDSQDENGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMISDLLNLSRIDNAATQMDIELTNFTAFITFILNRFDKMRGQDANKKYELVRNYPINSVW
VEIDTDKMTQVIDNLLNNAIKYSPDGGKITVSMKTTETQMIVSISDEGLGIPKADLPKIFDRFYRVDKARSREQGGTGLG
LAIAKEIVKQHNGFIWAKSQYGEGSTFTIVLPYDKDAVKEEDWDEEEIEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=194052 BFM96_RS07440 WP_068992437.1 1592774..1594126(+) (micB) [Streptococcus himalayensis strain HTS2]
ATGATTGAAACCATTAAAAGTTTTATAGTATCTAAGGATTTTATCTTTGTCCTGCTTATTTTGGGTTTTGTTCTGGTGAT
TGCTCTGTTAACCTTGGAGAATCGCAGGGATAATTTAAGAATTCGAGAGCTCAACCAAAAGGTCAAGGATTTGATTGCAG
GAGATTACTCTGAAGTGCTTGACATGCAGGGTGGGCCTGAGATTACGGACATTACCAATAGTTTAAATGACCTCTCTGAG
GTCATTCGTTTGACCCATGAAAATCTTGAGCAGGAAAGTAAGCGGCTAAACAGTATCTTATCTTACATGACAGACGGGGT
GCTTGCGACCAATCGTAGGGGCAAAATTATCATGATCAATGACATGGCAGCACGTCAGCTAGGGGTCAAAAAGGAAGAAG
CTGAAAATCTCAACATTTTACAGCTCCTAGGCATTGAAGAAGAGTACGAGCTGCGCGATTTGATTACCAAGGTTCCAGAT
GTGACCATTGATTCGCAGGATGAAAATGGAGAATACTTGAGTTTGCGAGTGCGGTTTGCTCTGATTCGTAGGGAATCTGG
CTTTATTTCTGGCTTGGTGGCTGTTCTACACGATACGACCGAGCAGGAAAAGGAAGAGCGAGAGCGACGACTCTTTGTCT
CGAATGTCAGCCACGAGCTGCGTACCCCCTTGACTAGTGTCAAGTCCTATCTAGAAGCACTGGATGAGGGAGCACTGAGT
GAGCCTGTGGCACCTGATTTTATCAAGGTATCGCTCGATGAGACCAATCGCATGATGCGGATGATTTCAGACTTACTCAA
TCTATCCCGCATTGACAATGCGGCCACCCAGATGGATATTGAGCTGACCAACTTTACGGCCTTTATCACCTTTATCCTCA
ATCGCTTTGATAAGATGAGGGGACAGGATGCGAATAAGAAATATGAGCTGGTTCGCAATTATCCGATTAACTCGGTCTGG
GTGGAGATTGATACGGACAAGATGACCCAAGTCATCGATAATCTCTTGAACAATGCTATTAAATACTCACCAGATGGAGG
GAAGATTACCGTTAGCATGAAAACGACCGAAACCCAGATGATTGTCTCCATCTCAGATGAAGGCTTGGGAATTCCAAAGG
CAGATTTGCCCAAGATTTTTGACCGCTTTTACCGAGTGGATAAGGCGAGAAGTCGGGAGCAAGGGGGGACTGGTCTGGGT
CTTGCTATCGCAAAGGAAATCGTCAAACAGCACAATGGCTTCATCTGGGCCAAAAGCCAGTACGGCGAAGGATCGACCTT
TACCATTGTCCTGCCTTATGACAAGGATGCGGTGAAAGAAGAGGACTGGGACGAGGAAGAAATAGAAGGATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS domain (PAS_9)

(105-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

80.866

97.556

0.789
  vicK Streptococcus mutans UA159

68.704

90.889

0.624

Multiple sequence alignment