Detailed information NTG0190481

Bioinformatically predicted

Overview

• Name: pilG
• Type: Machinery gene
• Locus tag: A6L41_RS11250
• Genome accession: NZ_CP016655
• Coordinates: 2170392..2171624 (-)
• Length: 410 a.a.
• NCBI ID: WP_002216405.1
• Uniprot ID: Q7DDR1
• Organism: Neisseria meningitidis strain M22772
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2165392..2176624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L41_RS11220 (A6L41_11220)	-	2165923..2166369 (+)	447	WP_002220271.1	DUF441 domain-containing protein	-
A6L41_RS11230 (A6L41_11230)	pilF	2166861..2168537 (+)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6L41_RS11235 (A6L41_11235)	-	2168622..2168831 (-)	210	WP_002216401.1	DNA gyrase inhibitor YacG	-
A6L41_RS11240 (A6L41_11240)	coaE	2168824..2169456 (-)	633	WP_002216402.1	dephospho-CoA kinase	-
A6L41_RS11245 (A6L41_11245)	pilD	2169458..2170318 (-)	861	WP_002241067.1	prepilin peptidase	Machinery gene
A6L41_RS11250 (A6L41_11250)	pilG	2170392..2171624 (-)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45273.29 Da
• Isoelectric Point: 9.9273

>NTDB_id=190481 A6L41_RS11250 WP_002216405.1 2170392..2171624(-) (pilG) [Neisseria meningitidis strain M22772]
MAKNGGFSLFAKKEKRFIFEGRHSASDKLVNGEVSAFTEEEARKKLAKRGIRPLQITRVKTSSKRKITQEDITVFTRQLS
TMIKAGLPLMQAFEIVARGHGNPSMTEMLMEIRGEVEQGSSLSRAFSNHPKYFDRFYCNLVAAGETGGVLESLLDKLAIY
KEKTQAIRKKVKTALTYPVSVIAVAIGLVFVMMIFVLPAFKEVYANMGAELPALTQTVMDMSDFFVSYGWMVLIALGFAI
YGFLKLKARSIKIQRRMDAILLRMPIFGDIVRKGTIARWGRTTATLIAAGVPLVDVLDSTAGAAGNLIYEEATREIRTRV
IQGLSMTSGMRATELFPNMMLQMSSIGEESGSLDDMLNKAAEFYEDEVDNAVGRLSAMMEPIIIVILGLVIGTLLVAMYL
PLFNLGNVVA

Nucleotide

• Length: 1233 bp

>NTDB_id=190481 A6L41_RS11250 WP_002216405.1 2170392..2171624(-) (pilG) [Neisseria meningitidis strain M22772]
ATGGCTAAAAACGGAGGATTTTCTTTGTTCGCAAAGAAAGAAAAACGCTTTATCTTTGAAGGCAGGCATTCCGCCTCCGA
CAAACTGGTCAACGGCGAAGTATCCGCGTTTACCGAAGAAGAGGCGCGCAAAAAACTGGCAAAACGCGGCATCCGCCCGT
TGCAGATTACCCGTGTGAAAACAAGCTCCAAGCGCAAAATCACACAAGAAGACATCACCGTTTTCACCCGCCAGCTGTCC
ACGATGATTAAAGCGGGCCTGCCGCTGATGCAGGCATTTGAAATCGTGGCGCGCGGACACGGCAACCCGTCTATGACGGA
AATGCTGATGGAAATCCGAGGCGAAGTGGAACAGGGCAGCTCGTTGAGCCGCGCATTCTCAAACCACCCGAAATATTTCG
ACCGCTTCTACTGCAACCTGGTTGCGGCAGGCGAAACGGGCGGCGTATTGGAAAGCCTGCTGGACAAATTGGCAATTTAC
AAAGAAAAAACCCAGGCCATCCGCAAAAAGGTAAAAACCGCACTGACCTATCCGGTATCCGTCATCGCCGTCGCCATCGG
TTTGGTATTCGTGATGATGATTTTCGTACTGCCCGCCTTTAAAGAAGTTTACGCCAATATGGGCGCGGAGCTTCCCGCAC
TGACCCAAACAGTGATGGATATGTCCGACTTTTTCGTCTCATACGGCTGGATGGTGCTGATCGCACTGGGCTTTGCCATA
TACGGCTTCCTTAAATTGAAGGCGCGTTCGATTAAAATCCAACGGCGTATGGATGCCATACTGCTGCGTATGCCGATTTT
CGGAGACATTGTCCGCAAAGGGACGATTGCCCGCTGGGGCAGGACGACAGCGACGCTGATTGCGGCAGGCGTGCCTTTGG
TCGATGTATTGGACTCCACTGCCGGCGCGGCGGGCAATTTAATCTATGAAGAAGCCACCCGGGAAATCCGTACGCGCGTC
ATCCAAGGTTTGTCTATGACTTCGGGGATGCGTGCGACGGAACTGTTCCCCAATATGATGTTGCAGATGTCTTCCATCGG
CGAGGAATCGGGTTCTTTGGACGATATGCTCAACAAAGCCGCCGAATTTTACGAAGACGAGGTGGACAATGCGGTCGGCA
GGCTGTCCGCTATGATGGAGCCGATCATTATCGTGATTTTAGGCTTGGTCATCGGCACGCTTCTGGTCGCCATGTATCTG
CCGCTGTTTAATTTGGGCAACGTGGTCGCCTGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (75-198)

• Type II secretion system (T2SS), protein F (T2SSF) (281-401)

3D structure

• AlphaFold DB: Q7DDR1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilG	Neisseria gonorrhoeae MS11	99.268	100	0.993
pilG	Neisseria meningitidis 44/76-A	98.537	100	0.985
pilC	Acinetobacter baumannii D1279779	47.487	97.073	0.461
pilC	Acinetobacter baylyi ADP1	45.614	97.317	0.444
pilC	Pseudomonas stutzeri DSM 10701	44.913	98.293	0.441
pilC	Legionella pneumophila strain ERS1305867	44.836	96.829	0.434
pilC	Vibrio cholerae strain A1552	41.045	98.049	0.402
pilC	Vibrio campbellii strain DS40M4	39.163	99.024	0.388