Detailed information NTG0187828

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: BBD27_RS02930
• Genome accession: NZ_CP016394
• Coordinates: 560390..561289 (-)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain ND07
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 555390..566289

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BBD27_RS11365 (BBD27_0583)	-	556243..556614 (+)	372	WP_224107488.1	hypothetical protein	-
BBD27_RS11370 (BBD27_0585)	-	557056..557535 (+)	480	WP_224107489.1	DUF4153 domain-containing protein	-
BBD27_RS02900 (BBD27_0586)	-	557681..558013 (-)	333	WP_024704184.1	DUF805 domain-containing protein	-
BBD27_RS02905 (BBD27_0587)	-	558121..558689 (-)	569	Protein_565	ATP-binding cassette domain-containing protein	-
BBD27_RS11375 (BBD27_0588)	comA	558744..558953 (-)	210	WP_002946147.1	hypothetical protein	Regulator
BBD27_RS11380 (BBD27_ps17)	-	558975..559691 (-)	717	Protein_567	ABC transporter transmembrane domain-containing protein	-
BBD27_RS11385	-	559721..560215 (-)	495	Protein_568	cysteine peptidase family C39 domain-containing protein	-
BBD27_RS02930 (BBD27_0590)	comR	560390..561289 (-)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
BBD27_RS02935 (BBD27_0591)	-	561484..562134 (-)	651	WP_011225447.1	phosphatase PAP2 family protein	-
BBD27_RS02940 (BBD27_0592)	-	562137..562694 (-)	558	WP_024704183.1	ECF transporter S component	-
BBD27_RS02945 (BBD27_0593)	-	563005..563544 (-)	540	WP_370869438.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
BBD27_RS02950 (BBD27_0594)	trkA	563804..565153 (+)	1350	WP_024704181.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=187828 BBD27_RS02930 WP_014607953.1 560390..561289(-) (comR) [Streptococcus thermophilus strain ND07]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=187828 BBD27_RS02930 WP_014607953.1 560390..561289(-) (comR) [Streptococcus thermophilus strain ND07]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418