Detailed information NTG0178893

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: AS891_RS05495
• Genome accession: NZ_CP015375
• Coordinates: 1065308..1065901 (-)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis subsp. subtilis strain KCTC 3135
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1060308..1070901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AS891_RS05480 (AS891_05475)	mdxK	1060634..1062907 (+)	2274	WP_003243769.1	maltose phosphorylase	-
AS891_RS05485 (AS891_05480)	malL	1062900..1064585 (+)	1686	WP_003243333.1	oligo-1,6-glucosidase	-
AS891_RS05490 (AS891_05485)	pgmB	1064582..1065262 (+)	681	WP_003228210.1	beta-phosphoglucomutase	-
AS891_RS05495 (AS891_05490)	clpP	1065308..1065901 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
AS891_RS05505 (AS891_05500)	cotR	1066531..1067493 (-)	963	WP_003243674.1	sporulation hydrolase CotR	-
AS891_RS05510 (AS891_05505)	cotNP	1067849..1069192 (+)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
AS891_RS05515 (AS891_05510)	yvdQ	1069444..1069956 (+)	513	WP_003243249.1	DUF3231 family protein	-
AS891_RS05520 (AS891_05515)	psmB	1069992..1070312 (-)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
AS891_RS05525 (AS891_05520)	psmA	1070312..1070647 (-)	336	WP_003242480.1	SMR family transporter	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=178893 AS891_RS05495 WP_003228214.1 1065308..1065901(-) (clpP) [Bacillus subtilis subsp. subtilis strain KCTC 3135]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=178893 AS891_RS05495 WP_003228214.1 1065308..1065901(-) (clpP) [Bacillus subtilis subsp. subtilis strain KCTC 3135]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA
CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538