Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V471_RS08315 Genome accession   NZ_CP015283
Coordinates   1778702..1779409 (-) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain ATCC 25975     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1773702..1784409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS08290 (V471_08175) - 1774370..1775584 (+) 1215 WP_084871391.1 aminoacyltransferase -
  V471_RS08295 (V471_08180) - 1775686..1775961 (-) 276 Protein_1577 ISL3 family transposase -
  V471_RS08300 (V471_08185) - 1776133..1776492 (-) 360 WP_045769141.1 YbaN family protein -
  V471_RS08305 (V471_08190) vicX 1776551..1777363 (-) 813 WP_084871512.1 MBL fold metallo-hydrolase Regulator
  V471_RS08310 (V471_08195) vicK 1777369..1778709 (-) 1341 WP_013990681.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V471_RS08315 (V471_08200) vicR 1778702..1779409 (-) 708 WP_002884978.1 response regulator YycF Regulator
  V471_RS08320 (V471_08205) - 1779695..1780462 (+) 768 WP_037611663.1 amino acid ABC transporter ATP-binding protein -
  V471_RS08325 (V471_08210) - 1780472..1781305 (+) 834 WP_084871393.1 transporter substrate-binding domain-containing protein -
  V471_RS08330 (V471_08215) - 1781323..1782021 (+) 699 WP_084871394.1 amino acid ABC transporter permease -
  V471_RS08335 (V471_08220) - 1782033..1782683 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  V471_RS08340 (V471_08225) - 1782870..1783637 (+) 768 WP_084871395.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=178320 V471_RS08315 WP_002884978.1 1778702..1779409(-) (vicR) [Streptococcus salivarius strain ATCC 25975]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=178320 V471_RS08315 WP_002884978.1 1778702..1779409(-) (vicR) [Streptococcus salivarius strain ATCC 25975]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCAATTATCATGCTTTCCGCT
AAGGATAGCGAGTTCGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACAAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTTGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTGATGACGCGTGAGCATTTGCTTGAAAC
TGTTTGGGGCTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment