Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V471_RS08310 Genome accession   NZ_CP015283
Coordinates   1777369..1778709 (-) Length   446 a.a.
NCBI ID   WP_013990681.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 25975     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1772369..1783709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS08280 (V471_08165) - 1772519..1773385 (-) 867 WP_004182606.1 GNAT family N-acetyltransferase -
  V471_RS08285 (V471_08170) yidA 1773564..1774370 (+) 807 WP_084871390.1 sugar-phosphatase -
  V471_RS08290 (V471_08175) - 1774370..1775584 (+) 1215 WP_084871391.1 aminoacyltransferase -
  V471_RS08295 (V471_08180) - 1775686..1775961 (-) 276 Protein_1577 ISL3 family transposase -
  V471_RS08300 (V471_08185) - 1776133..1776492 (-) 360 WP_045769141.1 YbaN family protein -
  V471_RS08305 (V471_08190) vicX 1776551..1777363 (-) 813 WP_084871512.1 MBL fold metallo-hydrolase Regulator
  V471_RS08310 (V471_08195) vicK 1777369..1778709 (-) 1341 WP_013990681.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V471_RS08315 (V471_08200) vicR 1778702..1779409 (-) 708 WP_002884978.1 response regulator YycF Regulator
  V471_RS08320 (V471_08205) - 1779695..1780462 (+) 768 WP_037611663.1 amino acid ABC transporter ATP-binding protein -
  V471_RS08325 (V471_08210) - 1780472..1781305 (+) 834 WP_084871393.1 transporter substrate-binding domain-containing protein -
  V471_RS08330 (V471_08215) - 1781323..1782021 (+) 699 WP_084871394.1 amino acid ABC transporter permease -
  V471_RS08335 (V471_08220) - 1782033..1782683 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  V471_RS08340 (V471_08225) - 1782870..1783637 (+) 768 WP_084871395.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50929.21 Da        Isoelectric Point: 5.1606

>NTDB_id=178319 V471_RS08310 WP_013990681.1 1777369..1778709(-) (vicK) [Streptococcus salivarius strain ATCC 25975]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=178319 V471_RS08310 WP_013990681.1 1777369..1778709(-) (vicK) [Streptococcus salivarius strain ATCC 25975]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTCAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CTCAGATGTCTATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCTAACGATGAGTTTGTGACCTTACGTGTTAACTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAAGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
ATCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTTGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCGTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCTATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment