Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   V471_RS02795 Genome accession   NZ_CP015283
Coordinates   540942..542177 (+) Length   411 a.a.
NCBI ID   WP_013991347.1    Uniprot ID   A0AB37CMH1
Organism   Streptococcus salivarius strain ATCC 25975     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 535942..547177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS02760 (V471_02735) - 536410..539004 (+) 2595 WP_049528176.1 YfhO family protein -
  V471_RS11365 (V471_02755) - 539559..540241 (-) 683 Protein_541 YoaK family protein -
  V471_RS02790 (V471_02760) rlmH 540257..540736 (-) 480 WP_014632473.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  V471_RS02795 (V471_02765) htrA 540942..542177 (+) 1236 WP_013991347.1 S1C family serine protease Regulator
  V471_RS02800 (V471_02770) spo0J 542244..543011 (+) 768 WP_014635206.1 ParB/RepB/Spo0J family partition protein Regulator
  V471_RS02805 (V471_02775) dnaA 543251..544615 (+) 1365 WP_049553505.1 chromosomal replication initiator protein DnaA -
  V471_RS02810 (V471_02780) dnaN 544770..545906 (+) 1137 WP_002886270.1 DNA polymerase III subunit beta -
  V471_RS02815 (V471_02785) - 545958..546149 (+) 192 WP_002886272.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42915.09 Da        Isoelectric Point: 4.6266

>NTDB_id=178280 V471_RS02795 WP_013991347.1 540942..542177(+) (htrA) [Streptococcus salivarius strain ATCC 25975]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=178280 V471_RS02795 WP_013991347.1 540942..542177(+) (htrA) [Streptococcus salivarius strain ATCC 25975]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTCGGTGGTTTGCTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCTGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATTCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(7-406)

Trypsin-like peptidase domain (Trypsin_2)

(118-263)

PDZ domain (PDZ_2)

(307-402)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.787

98.054

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.389

98.783

0.567
  htrA Streptococcus pneumoniae Rx1

54.279

99.513

0.54
  htrA Streptococcus pneumoniae R6

54.279

99.513

0.54
  htrA Streptococcus pneumoniae TIGR4

54.279

99.513

0.54
  htrA Streptococcus pneumoniae D39

54.279

99.513

0.54
  htrA Streptococcus mitis NCTC 12261

54.279

99.513

0.54

Multiple sequence alignment