Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NX99_RS05525 Genome accession   NZ_CP015282
Coordinates   1266127..1267026 (-) Length   299 a.a.
NCBI ID   WP_038675281.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1261127..1272026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS05510 (NX99_05425) - 1261956..1263347 (+) 1392 WP_084915047.1 DUF4153 domain-containing protein -
  NX99_RS05515 (NX99_05430) - 1263399..1263731 (-) 333 WP_014633880.1 DUF805 domain-containing protein -
  NX99_RS05520 (NX99_05435) comA 1263856..1265952 (-) 2097 WP_038675283.1 peptide cleavage/export ABC transporter Regulator
  NX99_RS05525 (NX99_05440) comR 1266127..1267026 (-) 900 WP_038675281.1 helix-turn-helix transcriptional regulator Regulator
  NX99_RS05530 (NX99_05445) - 1267206..1267856 (-) 651 WP_002883719.1 phosphatase PAP2 family protein -
  NX99_RS05535 (NX99_05450) - 1267859..1268416 (-) 558 WP_002883726.1 ECF transporter S component -
  NX99_RS05540 (NX99_05455) - 1268706..1269215 (-) 510 WP_084915049.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  NX99_RS05545 (NX99_05460) trkA 1269507..1270856 (+) 1350 WP_084915051.1 Trk system potassium transporter TrkA -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35169.68 Da        Isoelectric Point: 5.8538

>NTDB_id=178219 NX99_RS05525 WP_038675281.1 1266127..1267026(-) (comR) [Streptococcus salivarius strain ATCC 27945]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDKLSYIAKRLGKNMSDLLDHDNITIPDEYYE
MKNRLIKFPTYRNPERIKSKLALIEEVYEKFFELLPEEELLTLDILENILSFTNWEESPKVEEIYEDLFEQVKRKKKFST
NDLLVIDYYFFHLYGRKQFDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QFYSYKPSVFVLKAKYELLHKGNKKKAAENYDKAIMFASVLEDSVLEESIKAGKAADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=178219 NX99_RS05525 WP_038675281.1 1266127..1267026(-) (comR) [Streptococcus salivarius strain ATCC 27945]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGTCAGCAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTGCGTCAGTTAATTCGTATTGAAAAAGGGGAGTCACTCCCGTCTTTGGATAAATTATCTT
ATATTGCAAAACGTCTAGGAAAAAATATGTCTGATCTATTGGATCATGACAATATTACCATTCCTGACGAATATTATGAG
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAATCCAGAAAGAATAAAGTCTAAACTTGCCTTAATTGAGGAAGT
CTATGAGAAATTCTTTGAACTTCTTCCAGAAGAAGAGTTGTTAACTCTAGATATTTTGGAAAATATTTTGAGTTTTACTA
ATTGGGAGGAGAGCCCAAAGGTTGAAGAAATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAAGAAATTCTCAACT
AACGATTTATTAGTTATTGACTATTATTTCTTCCATCTCTATGGAAGAAAACAGTTTGACAAAAAACTTTTTGAAAGGAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGACGATGTCTATAATATTGTTTTATTTAATGATTTGATGGCTATCG
CTGCTTTGAAGATTTTTCACAATTCCTTTTCAGACTTCTTAACAGTTGTGGATAAAGCATTAGCCGTTATAGAAAAATCA
CAATTCTATAGCTATAAACCTAGTGTTTTTGTTCTCAAAGCTAAATATGAACTTCTGCATAAGGGAAATAAGAAAAAGGC
TGCAGAGAATTACGATAAGGCCATAATGTTTGCTTCCGTTTTAGAAGACTCGGTTTTAGAAGAAAGTATAAAAGCAGGGA
AAGCGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

97.659

100

0.977
  comR Streptococcus salivarius SK126

96.99

100

0.97
  comR Streptococcus thermophilus LMG 18311

94.314

100

0.943
  comR Streptococcus thermophilus LMD-9

93.645

100

0.936
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.809

100

0.428
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.475

100

0.425

Multiple sequence alignment