Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NX99_RS05520 Genome accession   NZ_CP015282
Coordinates   1263856..1265952 (-) Length   698 a.a.
NCBI ID   WP_038675283.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1258856..1270952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS05500 (NX99_05415) - 1259656..1260558 (-) 903 WP_002883785.1 MetQ/NlpA family ABC transporter substrate-binding protein -
  NX99_RS05505 (NX99_05420) - 1260718..1261566 (-) 849 WP_014633606.1 amino acid ABC transporter substrate-binding protein -
  NX99_RS05510 (NX99_05425) - 1261956..1263347 (+) 1392 WP_084915047.1 DUF4153 domain-containing protein -
  NX99_RS05515 (NX99_05430) - 1263399..1263731 (-) 333 WP_014633880.1 DUF805 domain-containing protein -
  NX99_RS05520 (NX99_05435) comA 1263856..1265952 (-) 2097 WP_038675283.1 peptide cleavage/export ABC transporter Regulator
  NX99_RS05525 (NX99_05440) comR 1266127..1267026 (-) 900 WP_038675281.1 helix-turn-helix transcriptional regulator Regulator
  NX99_RS05530 (NX99_05445) - 1267206..1267856 (-) 651 WP_002883719.1 phosphatase PAP2 family protein -
  NX99_RS05535 (NX99_05450) - 1267859..1268416 (-) 558 WP_002883726.1 ECF transporter S component -
  NX99_RS05540 (NX99_05455) - 1268706..1269215 (-) 510 WP_084915049.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  NX99_RS05545 (NX99_05460) trkA 1269507..1270856 (+) 1350 WP_084915051.1 Trk system potassium transporter TrkA -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78465.38 Da        Isoelectric Point: 8.9687

>NTDB_id=178218 NX99_RS05520 WP_038675283.1 1263856..1265952(-) (comA) [Streptococcus salivarius strain ATCC 27945]
MSKYPYISQVDQRDCGVAALSMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLAMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAIGHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKELLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLTKIKRTMIFIAHRHSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=178218 NX99_RS05520 WP_038675283.1 1263856..1265952(-) (comA) [Streptococcus salivarius strain ATCC 27945]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGTCCATGATTCTTAAACACTA
TGGTTCGTCTTATAGTTTGGCCTATTTGCGGGAGTTGGCTCAGACCTCTCGGGAAGGAACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCCATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGACTGCAACATTATTATACGGTGTTTGGTCAAATCAAAGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGATTGATTGCAGTCATTGTCTTACTGAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTGACAATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCCTACCGATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACATCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCAATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCCCTTATTTTACAAAATCAGTCACTTTTTGTGATGACACTCACGGTAGTTCCTCTTTATGTGTTAATCATT
TTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAGAGACGGTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCTAAGTGGCAATTAACGCAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGCCATGGAAGGACAGCTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCAAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCCTTTAAACAACTTGCTCTT
AAGGGTGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
TGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTAGCGAAAATGTTGTCGGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTGGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACTGGAACCATTTTAGAAAATCTGCTGTTAGGATTTGAAGGAGAAGTTGACGAGAAAGAACTTCTTAAGGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAGGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCGAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTACTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
TCATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter (ABC_tran)

(494-640)

ABC transporter transmembrane region (ABC_membrane)

(167-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.69

98.997

0.532
  comA Streptococcus gordonii str. Challis substr. CH1

53.017

99.713

0.529
  comA Streptococcus mitis NCTC 12261

53.256

98.997

0.527
  comA Streptococcus pneumoniae Rx1

53.111

98.997

0.526
  comA Streptococcus pneumoniae D39

53.111

98.997

0.526
  comA Streptococcus pneumoniae R6

53.111

98.997

0.526
  comA Streptococcus pneumoniae TIGR4

52.967

98.997

0.524
  comA/nlmT Streptococcus mutans UA159

50

98.854

0.494

Multiple sequence alignment