Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   NX99_RS02370 Genome accession   NZ_CP015282
Coordinates   610329..611036 (-) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain ATCC 27945     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 605329..616036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS02345 (NX99_02320) yidA 605683..606492 (+) 810 WP_002890845.1 sugar-phosphatase -
  NX99_RS02350 (NX99_02325) - 606494..607708 (+) 1215 WP_084914610.1 aminoacyltransferase -
  NX99_RS02355 (NX99_02330) - 607760..608119 (-) 360 WP_037611660.1 YbaN family protein -
  NX99_RS02360 (NX99_02335) vicX 608178..608987 (-) 810 WP_126405093.1 MBL fold metallo-hydrolase Regulator
  NX99_RS02365 (NX99_02340) vicK 608993..610336 (-) 1344 WP_038675887.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NX99_RS02370 (NX99_02345) vicR 610329..611036 (-) 708 WP_002884978.1 response regulator YycF Regulator
  NX99_RS02375 (NX99_02350) - 611336..612103 (+) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  NX99_RS02380 (NX99_02355) - 612113..612946 (+) 834 WP_037611665.1 transporter substrate-binding domain-containing protein -
  NX99_RS02385 (NX99_02360) - 612964..613662 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  NX99_RS02390 (NX99_02365) - 613674..614324 (+) 651 WP_037601175.1 amino acid ABC transporter permease -
  NX99_RS02395 (NX99_02370) - 614510..615277 (+) 768 WP_060775856.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=178201 NX99_RS02370 WP_002884978.1 610329..611036(-) (vicR) [Streptococcus salivarius strain ATCC 27945]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=178201 NX99_RS02370 WP_002884978.1 610329..611036(-) (vicR) [Streptococcus salivarius strain ATCC 27945]
ATGAAAAAAATTCTAGTTGTTGATGACGAAAGACCGATTTCGGACATCATCAAGTTTAACCTGACAAAAGAAGGTTATGA
AGTGGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCATACACCAATTATCATGCTCTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGACTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACCTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTTGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTGATGACGCGTGAGCATTTGCTTGAAAC
TGTTTGGGGCTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment