Detailed information NTG0177890

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: A4265_RS01475
• Genome accession: NZ_CP015238
• Coordinates: 283668..284210 (+)
• Length: 180 a.a.
• NCBI ID: WP_076612425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NS53
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	284830..285898	283668..284210	flank	620

Gene organization within MGE regions

Location: 283668..285898

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4265_RS01475 (A4265_01350)	comX/sigX/comX2/sigX2	283668..284210 (+)	543	WP_076612425.1	competence protein ComX	Regulator
A4265_RS01480 (A4265_01355)	-	284830..285898 (+)	1069	Protein_262	ISAs1 family transposase	-

Sequence

Protein

• Length: 180 a.a.
• Molecular weight: 21927.70 Da
• Isoelectric Point: 10.0375

>NTDB_id=177890 A4265_RS01475 WP_076612425.1 283668..284210(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NS53]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYLELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFA

Nucleotide

• Length: 543 bp

>NTDB_id=177890 A4265_RS01475 WP_076612425.1 283668..284210(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NS53]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCTAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTTCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCATAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	99.444	100	0.994
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	99.444	100	0.994
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	98.889	100	0.989
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	98.889	100	0.989
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	98.889	100	0.989
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	98.889	100	0.989
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.667	83.333	0.406
comX	Streptococcus sobrinus strain NIDR 6715-7	46.358	83.889	0.389
comX/sigX	Streptococcus mutans UA159	44.667	83.333	0.372