Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   A4A60_RS18710 Genome accession   NZ_CP015222
Coordinates   3514742..3515335 (+) Length   197 a.a.
NCBI ID   WP_003228214.1    Uniprot ID   A0A199WEF2
Organism   Bacillus subtilis strain HRBS-10TDI13     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context


Location: 3509742..3520335
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4A60_RS18680 (A4A60_18690) aspP 3510716..3512278 (+) 1563 WP_003228228.1 aspartate/proton symporter AspP -
  A4A60_RS18685 (A4A60_18695) - 3512373..3512957 (+) 585 WP_003228226.1 TetR family transcriptional regulator -
  A4A60_RS18690 (A4A60_18700) psmA 3513039..3513374 (+) 336 WP_014480966.1 SMR family transporter -
  A4A60_RS18695 (A4A60_18705) psmB 3513374..3513694 (+) 321 WP_014480967.1 QacE family quaternary ammonium compound efflux SMR transporter -
  A4A60_RS18700 (A4A60_18710) yvdQ 3513730..3514238 (-) 509 Protein_3641 DUF3231 family protein -
  A4A60_RS18710 (A4A60_18720) clpP 3514742..3515335 (+) 594 WP_003228214.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  A4A60_RS18715 (A4A60_18725) pgmB 3515398..3516072 (-) 675 WP_014480982.1 beta-phosphoglucomutase -
  A4A60_RS18720 (A4A60_18730) malL 3516069..3517754 (-) 1686 WP_033881298.1 oligo-1,6-glucosidase -
  A4A60_RS18725 (A4A60_18735) mdxK 3517747..3520020 (-) 2274 WP_014480985.1 maltose phosphorylase -

Sequence


Protein


Download         Length: 197 a.a.        Molecular weight: 21682.00 Da        Isoelectric Point: 4.9416

>NTDB_id=177682 A4A60_RS18710 WP_003228214.1 3514742..3515335(+) (clpP) [Bacillus subtilis strain HRBS-10TDI13]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide


Download         Length: 594 bp        

>NTDB_id=177682 A4A60_RS18710 WP_003228214.1 3514742..3515335(+) (clpP) [Bacillus subtilis strain HRBS-10TDI13]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCATCAATGGGCGCTTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains


Predicted by InterproScan.

(13-192)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A199WEF2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

100

100

1

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.617

95.431

0.655

  clpP Streptococcus thermophilus LMG 18311

58.163

99.492

0.579

  clpP Streptococcus thermophilus LMD-9

58.163

99.492

0.579

  clpP Streptococcus pneumoniae D39

57.812

97.462

0.563

  clpP Streptococcus pneumoniae Rx1

57.812

97.462

0.563

  clpP Streptococcus pneumoniae R6

57.812

97.462

0.563

  clpP Streptococcus pneumoniae TIGR4

57.812

97.462

0.563

  clpP Lactococcus lactis subsp. cremoris KW2

57.895

96.447

0.558

  clpP Streptococcus pyogenes JRS4

56.122

99.492

0.558

  clpP Streptococcus pyogenes MGAS315

56.122

99.492

0.558

  clpP Streptococcus mutans UA159

54.822

100

0.548

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

55.789

96.447

0.538


Multiple sequence alignment