Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   BtBc_RS26915 Genome accession   NZ_CP015150
Coordinates   5261009..5261590 (+) Length   193 a.a.
NCBI ID   WP_001049162.1    Uniprot ID   A0A9W5QPC2
Organism   Bacillus thuringiensis strain Bc601     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 5211197..5263140 5261009..5261590 within 0


Gene organization within MGE regions


Location: 5211197..5263140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BtBc_RS26570 (BtBc_26570) cggR 5211197..5212225 (-) 1029 WP_001258185.1 gapA transcriptional regulator CggR -
  BtBc_RS26575 (BtBc_26575) - 5212361..5212606 (-) 246 WP_000869730.1 glutaredoxin family protein -
  BtBc_RS26580 (BtBc_26580) rpoN 5212616..5213923 (-) 1308 WP_000647955.1 RNA polymerase factor sigma-54 -
  BtBc_RS26585 (BtBc_26585) - 5214486..5215313 (+) 828 WP_000412580.1 helix-turn-helix domain-containing protein -
  BtBc_RS26590 (BtBc_26590) - 5215329..5215622 (-) 294 WP_001273481.1 YolD-like family protein -
  BtBc_RS26595 (BtBc_26595) - 5215647..5215865 (-) 219 WP_001016121.1 hypothetical protein -
  BtBc_RS26600 (BtBc_26600) - 5216009..5216575 (+) 567 WP_000742864.1 hypothetical protein -
  BtBc_RS26605 (BtBc_26605) - 5216754..5216972 (-) 219 WP_000734384.1 hypothetical protein -
  BtBc_RS26610 (BtBc_26610) - 5216972..5218087 (-) 1116 WP_000993515.1 Rap family tetratricopeptide repeat protein -
  BtBc_RS26615 (BtBc_26615) - 5218291..5219226 (-) 936 WP_000405783.1 N-acetylmuramoyl-L-alanine amidase -
  BtBc_RS26620 (BtBc_26620) - 5219524..5220717 (+) 1194 WP_000499524.1 IS110 family transposase -
  BtBc_RS26625 (BtBc_26625) - 5220779..5221222 (-) 444 WP_042991251.1 phage holin family protein -
  BtBc_RS26630 (BtBc_26630) - 5221517..5222710 (+) 1194 WP_000499524.1 IS110 family transposase -
  BtBc_RS26635 (BtBc_26635) - 5222831..5223202 (-) 372 WP_016090170.1 hypothetical protein -
  BtBc_RS26640 (BtBc_26640) - 5223219..5227601 (-) 4383 WP_015382502.1 phage tail spike protein -
  BtBc_RS26645 (BtBc_26645) - 5227598..5229067 (-) 1470 WP_015382503.1 distal tail protein Dit -
  BtBc_RS26650 (BtBc_26650) - 5229109..5231490 (-) 2382 WP_002133928.1 hypothetical protein -
  BtBc_RS26655 (BtBc_26655) - 5231768..5233003 (-) 1236 WP_000897021.1 hypothetical protein -
  BtBc_RS26660 (BtBc_26660) - 5233234..5233596 (-) 363 WP_000415931.1 hypothetical protein -
  BtBc_RS26665 (BtBc_26665) - 5233603..5234196 (-) 594 WP_001004920.1 major tail protein -
  BtBc_RS26670 (BtBc_26670) - 5234197..5234532 (-) 336 WP_000219080.1 hypothetical protein -
  BtBc_RS26675 (BtBc_26675) - 5234529..5234873 (-) 345 WP_000997537.1 HK97 gp10 family phage protein -
  BtBc_RS26680 (BtBc_26680) - 5234875..5235225 (-) 351 WP_001247297.1 phage head closure protein -
  BtBc_RS26685 (BtBc_26685) - 5235227..5235520 (-) 294 WP_000361981.1 hypothetical protein -
  BtBc_RS26690 (BtBc_26690) - 5235533..5236675 (-) 1143 WP_086401347.1 phage major capsid protein -
  BtBc_RS26695 (BtBc_26695) - 5236726..5237451 (-) 726 WP_000791073.1 head maturation protease, ClpP-related -
  BtBc_RS26700 (BtBc_26700) - 5237441..5238592 (-) 1152 WP_000118683.1 phage portal protein -
  BtBc_RS26705 (BtBc_26705) - 5238613..5240298 (-) 1686 WP_000595321.1 terminase large subunit -
  BtBc_RS26710 (BtBc_26710) - 5240295..5240606 (-) 312 WP_000301150.1 P27 family phage terminase small subunit -
  BtBc_RS26715 (BtBc_26715) - 5240731..5241066 (-) 336 WP_000666398.1 HNH endonuclease -
  BtBc_RS26720 (BtBc_26720) - 5241032..5241406 (-) 375 WP_001177571.1 hypothetical protein -
  BtBc_RS26725 (BtBc_26725) - 5241397..5241654 (-) 258 WP_000378699.1 hypothetical protein -
  BtBc_RS26730 (BtBc_26730) - 5241661..5241870 (-) 210 WP_001177575.1 hypothetical protein -
  BtBc_RS26735 (BtBc_26735) - 5241939..5242373 (-) 435 WP_001002014.1 hypothetical protein -
  BtBc_RS26740 (BtBc_26740) - 5242379..5242582 (-) 204 WP_000343502.1 hypothetical protein -
  BtBc_RS26745 (BtBc_26745) - 5242596..5242820 (-) 225 WP_000650576.1 hypothetical protein -
  BtBc_RS32970 - 5243057..5243182 (+) 126 WP_306426678.1 type II toxin-antitoxin system HicA family toxin -
  BtBc_RS26750 (BtBc_26750) - 5243234..5243653 (+) 420 WP_000711194.1 type II toxin-antitoxin system HicB family antitoxin -
  BtBc_RS26755 (BtBc_26755) - 5244037..5244438 (-) 402 WP_003308641.1 hypothetical protein -
  BtBc_RS26760 (BtBc_26760) - 5244476..5244802 (-) 327 WP_015670520.1 hypothetical protein -
  BtBc_RS26765 (BtBc_26765) recU 5244799..5245326 (-) 528 WP_000540086.1 Holliday junction resolvase RecU -
  BtBc_RS26770 (BtBc_26770) - 5245362..5245673 (-) 312 WP_000590881.1 hypothetical protein -
  BtBc_RS26775 (BtBc_26775) - 5245718..5246413 (-) 696 WP_000858114.1 hypothetical protein -
  BtBc_RS26780 (BtBc_26780) - 5246449..5246703 (-) 255 WP_000520932.1 hypothetical protein -
  BtBc_RS26785 (BtBc_26785) - 5246786..5247579 (-) 794 Protein_5318 prohibitin family protein -
  BtBc_RS33905 - 5247581..5247721 (-) 141 WP_000492043.1 hypothetical protein -
  BtBc_RS26790 (BtBc_26790) - 5247726..5248016 (-) 291 WP_001268031.1 hypothetical protein -
  BtBc_RS26795 (BtBc_26795) - 5248075..5248509 (-) 435 WP_000775809.1 hypothetical protein -
  BtBc_RS26800 (BtBc_26800) - 5248548..5249105 (-) 558 WP_001245738.1 hypothetical protein -
  BtBc_RS26805 (BtBc_26805) - 5249129..5249359 (-) 231 WP_000139235.1 hypothetical protein -
  BtBc_RS26810 (BtBc_26810) - 5249352..5249831 (-) 480 WP_000933908.1 hypothetical protein -
  BtBc_RS26815 (BtBc_26815) - 5249843..5250796 (-) 954 WP_000510889.1 DnaD domain protein -
  BtBc_RS26820 (BtBc_26820) - 5250890..5251231 (-) 342 WP_002133909.1 hypothetical protein -
  BtBc_RS26825 (BtBc_26825) - 5251161..5251376 (-) 216 WP_000355713.1 hypothetical protein -
  BtBc_RS26830 (BtBc_26830) - 5251376..5252089 (-) 714 WP_015382506.1 hypothetical protein -
  BtBc_RS26835 (BtBc_26835) - 5252107..5252550 (-) 444 WP_000453495.1 hypothetical protein -
  BtBc_RS26840 (BtBc_26840) - 5252577..5252765 (-) 189 WP_001187283.1 hypothetical protein -
  BtBc_RS26845 (BtBc_26845) - 5252777..5253532 (-) 756 WP_001016247.1 phage regulatory protein -
  BtBc_RS33910 - 5253547..5253702 (-) 156 WP_000788383.1 hypothetical protein -
  BtBc_RS26850 (BtBc_26850) - 5253886..5254119 (-) 234 WP_000711864.1 DUF771 domain-containing protein -
  BtBc_RS26855 (BtBc_26855) - 5254155..5254385 (-) 231 WP_000216290.1 helix-turn-helix transcriptional regulator -
  BtBc_RS26860 (BtBc_26860) - 5254550..5254942 (+) 393 WP_002133807.1 helix-turn-helix transcriptional regulator -
  BtBc_RS26865 (BtBc_26865) - 5254953..5255420 (+) 468 WP_001037137.1 hypothetical protein -
  BtBc_RS26870 (BtBc_26870) - 5255451..5256587 (+) 1137 WP_000135757.1 tyrosine-type recombinase/integrase -
  BtBc_RS26880 (BtBc_26880) - 5257002..5257208 (+) 207 WP_000216166.1 DUF1657 domain-containing protein -
  BtBc_RS26885 (BtBc_26885) - 5257302..5257790 (+) 489 WP_001226064.1 YhcN/YlaJ family sporulation lipoprotein -
  BtBc_RS26890 (BtBc_26890) spoVAC 5257820..5258296 (+) 477 WP_000095408.1 stage V sporulation protein AC -
  BtBc_RS26895 (BtBc_26895) spoVAD 5258297..5259313 (+) 1017 WP_000938972.1 stage V sporulation protein AD -
  BtBc_RS26900 (BtBc_26900) spoVAE 5259310..5259660 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  BtBc_RS26905 (BtBc_26905) - 5259672..5259878 (+) 207 WP_000215909.1 DUF1657 domain-containing protein -
  BtBc_RS26910 (BtBc_26910) - 5259899..5260768 (+) 870 WP_000018924.1 DUF421 domain-containing protein -
  BtBc_RS26915 (BtBc_26915) clpP 5261009..5261590 (+) 582 WP_001049162.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  BtBc_RS26920 (BtBc_26920) - 5261918..5262166 (-) 249 WP_000250307.1 HPr family phosphocarrier protein -
  BtBc_RS26925 (BtBc_26925) whiA 5262190..5263140 (-) 951 WP_000006560.1 DNA-binding protein WhiA -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21419.67 Da        Isoelectric Point: 5.0423

>NTDB_id=177163 BtBc_RS26915 WP_001049162.1 5261009..5261590(+) (clpP) [Bacillus thuringiensis strain Bc601]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAEKALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=177163 BtBc_RS26915 WP_001049162.1 5261009..5261590(+) (clpP) [Bacillus thuringiensis strain Bc601]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGTGCAATTGATGACAACGTAGCTAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTACATCAACAGCCCTGGTGGTTCTATCACAGCAGGTATGGCAATCTATGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCAGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTATGCACTTCCAAACAGTGAAGTAATGATTCACCAACCACTTGGCGGAGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAACTAAACCAAATTCTTGCTGACCGCACTGGTCAA
CCACTTGAAGTACTACAACGCGACACAGACCGCGACAACTTCATGACAGCAGAAAAAGCTTTAGAATACGGTTTAATCGA
TAAAATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

90.104

99.482

0.896
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.021

97.409

0.653
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Lactococcus lactis subsp. cremoris KW2

58.854

99.482

0.585
  clpP Streptococcus pneumoniae D39

57.292

99.482

0.57
  clpP Streptococcus pneumoniae Rx1

57.292

99.482

0.57
  clpP Streptococcus pneumoniae R6

57.292

99.482

0.57
  clpP Streptococcus pneumoniae TIGR4

57.292

99.482

0.57
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

56.771

99.482

0.565
  clpP Streptococcus pyogenes JRS4

55.729

99.482

0.554
  clpP Streptococcus pyogenes MGAS315

55.729

99.482

0.554
  clpP Streptococcus mutans UA159

55.44

100

0.554

Multiple sequence alignment