Detailed information NTG0174502

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: A2G56_RS09735
• Genome accession: NZ_CP014835
• Coordinates: 2127585..2128256 (+)
• Length: 223 a.a.
• NCBI ID: WP_062712117.1
• Uniprot ID: -
• Organism: Streptococcus halotolerans strain HTS9
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2122585..2133256

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2G56_RS09705	-	2122863..2124455 (+)	1593	WP_062712102.1	DEAD/DEAH box helicase	-
A2G56_RS09710	-	2124578..2124838 (-)	261	WP_062712104.1	GIY-YIG nuclease family protein	-
A2G56_RS09715	-	2124831..2125595 (-)	765	WP_062712107.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
A2G56_RS09720	-	2125853..2126383 (+)	531	WP_062712109.1	isoprenylcysteine carboxyl methyltransferase family protein	-
A2G56_RS09725	-	2126418..2126606 (-)	189	WP_062712112.1	hypothetical protein	-
A2G56_RS09730	-	2126766..2127515 (+)	750	WP_062712115.1	lysophospholipid acyltransferase family protein	-
A2G56_RS09735	comEA/celA/cilE	2127585..2128256 (+)	672	WP_062712117.1	helix-hairpin-helix domain-containing protein	Machinery gene
A2G56_RS09740	comEC/celB	2128249..2130480 (+)	2232	WP_062712120.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A2G56_RS09745	-	2130698..2131348 (-)	651	WP_062712123.1	amino acid ABC transporter permease	-
A2G56_RS09750	-	2131357..2132055 (-)	699	WP_062712127.1	amino acid ABC transporter permease	-
A2G56_RS09755	-	2132075..2132902 (-)	828	WP_062712129.1	transporter substrate-binding domain-containing protein	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 23911.85 Da
• Isoelectric Point: 4.4843

>NTDB_id=174502 A2G56_RS09735 WP_062712117.1 2127585..2128256(+) (comEA/celA/cilE) [Streptococcus halotolerans strain HTS9]
MFEDMLEKIHTNKVVVGLGGLVILLLMTCLFLLRNPSKETQEELLPSWSGQSETISSTTMPSKEGSQAEKSQSSTMITVD
VKGAVKKPGVYDLPSGSRVNDAILLAGGLREDADRKSVNFAQKLSDEGIVYVASQGENISVINSSVAPQNSTDSSEVSTG
KVDLNRATLADLQTISGIGQKRAQDIIDYRDSNGGFKSVDDLSNVSGIGDKTLEKLREEVTVD

Nucleotide

• Length: 672 bp

>NTDB_id=174502 A2G56_RS09735 WP_062712117.1 2127585..2128256(+) (comEA/celA/cilE) [Streptococcus halotolerans strain HTS9]
ATGTTTGAGGATATGTTAGAAAAAATCCATACCAACAAAGTTGTCGTGGGACTGGGGGGGTTAGTTATTTTACTGCTGAT
GACATGTCTTTTTCTTTTGAGGAATCCTTCAAAGGAAACTCAGGAAGAGCTTTTACCATCATGGTCAGGACAGTCAGAAA
CCATCAGTAGCACAACGATGCCCTCGAAAGAAGGCTCTCAAGCGGAAAAATCACAATCATCGACGATGATCACGGTTGAT
GTTAAGGGAGCCGTCAAAAAGCCAGGCGTTTATGACTTACCGAGTGGTAGTCGTGTTAATGATGCTATTTTATTGGCAGG
TGGATTAAGAGAAGACGCGGATCGAAAGTCTGTCAATTTTGCTCAAAAATTAAGTGATGAAGGCATTGTTTATGTGGCGA
GTCAGGGTGAAAATATCTCAGTCATAAATTCAAGTGTTGCTCCTCAAAACTCAACGGATTCTTCAGAAGTCTCTACCGGC
AAAGTCGACCTTAATAGGGCTACACTAGCTGATTTACAGACGATTTCTGGTATCGGTCAAAAACGGGCTCAGGACATCAT
AGATTATCGTGATAGCAATGGTGGTTTTAAATCGGTTGATGACCTGTCAAATGTTTCTGGTATTGGTGATAAGACTCTTG
AAAAGCTGCGTGAGGAAGTGACGGTTGATTGA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (79-125)

• Helix-hairpin-helix motif (HHH_3) (158-221)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	49.123	100	0.502
comEA/celA/cilE	Streptococcus pneumoniae D39	49.123	100	0.502
comEA/celA/cilE	Streptococcus pneumoniae R6	49.123	100	0.502
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	47.826	100	0.493
comEA/celA/cilE	Streptococcus mitis NCTC 12261	46.957	100	0.484
comEA/celA/cilE	Streptococcus mitis SK321	46.087	100	0.475
comEA	Streptococcus thermophilus LMD-9	43.644	100	0.462
comEA	Latilactobacillus sakei subsp. sakei 23K	33.878	100	0.372