Detailed information NTG0174503

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: A2G56_RS09740
• Genome accession: NZ_CP014835
• Coordinates: 2128249..2130480 (+)
• Length: 743 a.a.
• NCBI ID: WP_062712120.1
• Uniprot ID: -
• Organism: Streptococcus halotolerans strain HTS9
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2123249..2135480

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2G56_RS09710	-	2124578..2124838 (-)	261	WP_062712104.1	GIY-YIG nuclease family protein	-
A2G56_RS09715	-	2124831..2125595 (-)	765	WP_062712107.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
A2G56_RS09720	-	2125853..2126383 (+)	531	WP_062712109.1	isoprenylcysteine carboxyl methyltransferase family protein	-
A2G56_RS09725	-	2126418..2126606 (-)	189	WP_062712112.1	hypothetical protein	-
A2G56_RS09730	-	2126766..2127515 (+)	750	WP_062712115.1	lysophospholipid acyltransferase family protein	-
A2G56_RS09735	comEA/celA/cilE	2127585..2128256 (+)	672	WP_062712117.1	helix-hairpin-helix domain-containing protein	Machinery gene
A2G56_RS09740	comEC/celB	2128249..2130480 (+)	2232	WP_062712120.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A2G56_RS09745	-	2130698..2131348 (-)	651	WP_062712123.1	amino acid ABC transporter permease	-
A2G56_RS09750	-	2131357..2132055 (-)	699	WP_062712127.1	amino acid ABC transporter permease	-
A2G56_RS09755	-	2132075..2132902 (-)	828	WP_062712129.1	transporter substrate-binding domain-containing protein	-
A2G56_RS09760	-	2132919..2133701 (-)	783	WP_062712131.1	amino acid ABC transporter ATP-binding protein	-
A2G56_RS09765	vicR	2133937..2134644 (+)	708	WP_062712133.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 84440.15 Da
• Isoelectric Point: 9.6412

>NTDB_id=174503 A2G56_RS09740 WP_062712120.1 2128249..2130480(+) (comEC/celB) [Streptococcus halotolerans strain HTS9]
MIETRLLKPMYLAFLVTLTYFIIFTKSWVAIFLAVVAFICLIKQYQKKTIWQIMLIIAIFSLYFVWIDHRQHTLEKNLPS
QVSELRLIPDSLSVDGDLLSGRAVQGHQTYQFYYQLQTVSEKKYFQELNQVVRLNVVAKVEKPVGQRNFKGFDYAAYLKR
EGIYGIAQVTAITSIKVAQPNNPIEWVRLWRRQLLVHINQSFPAPMQHYMTGLLLGYLDKAFDEMSDIYTDLGIIHLFAL
SGMQVGFFIGIFRTILLRLGILREHFSYFLLPFSFLYAGLTGFTVSVVRSLLQTILGQFGFRKWDNLGLTMLIFFILSPH
FLETVGGVLSFAYAFILSRLNLESLSGRRKVVAESLVLSFGILPLLIFYFGSFQPLSILLTACFSVIFDVLLLPLLSLVL
LASPLMSLSFCNPLFLVLESVIKWTAQLSPKPLVFGSPNVVVLILILAFLAALHDFWKEKKLRYALLLASICLFVLTKHP
LENEVTVMDVGQGDSILIRDMGGKTLLIDTGGRVDFTQKEAWRNRQTRANAEKTSIPYLKSRGISTIDQLLITHTDTDHM
GDLSILAKHFKIKEILISPGAMTKSSFVKELQALNIKVRLVHAGDRFPIMGTSLHVLYPWSQGDGGNNDSLVLYGKLLDK
RFLFTGDLEVEGEKALLARYPNLPVDVLKAGHHGSKGSSDPEFLRHINATEALISAGLNNRYHHPNDETLERFDVEKMTV
YRTDQEGAIRYRGMKNWRVETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=174503 A2G56_RS09740 WP_062712120.1 2128249..2130480(+) (comEC/celB) [Streptococcus halotolerans strain HTS9]
TTGATTGAGACTAGATTGTTAAAGCCAATGTATTTGGCTTTTTTAGTAACGTTGACCTACTTTATTATTTTCACCAAATC
TTGGGTTGCTATTTTTTTAGCAGTGGTTGCTTTCATATGCCTTATCAAGCAATACCAGAAAAAGACGATTTGGCAGATCA
TGCTTATAATCGCTATATTTTCGCTGTATTTTGTTTGGATTGATCATAGACAGCATACATTAGAGAAGAACCTTCCTAGC
CAAGTTTCAGAACTACGTCTCATTCCTGATAGCCTTTCAGTAGATGGTGATTTACTTTCAGGACGTGCTGTTCAGGGACA
CCAAACGTATCAGTTTTATTATCAATTGCAGACGGTATCGGAGAAAAAGTATTTTCAAGAGCTCAACCAAGTGGTTCGTT
TAAATGTAGTCGCAAAAGTTGAGAAACCTGTTGGTCAACGCAATTTCAAAGGATTTGACTATGCCGCTTACTTGAAGCGT
GAGGGGATTTACGGCATTGCGCAAGTCACTGCTATTACGTCAATTAAAGTGGCACAGCCTAACAACCCCATCGAGTGGGT
AAGATTGTGGCGACGCCAGCTTCTAGTTCACATCAATCAGAGCTTTCCTGCTCCCATGCAGCATTATATGACAGGGCTCT
TATTGGGGTATTTGGACAAGGCTTTTGATGAGATGAGTGATATATACACAGATTTGGGGATTATTCATCTCTTTGCCCTT
TCAGGTATGCAAGTAGGTTTTTTTATAGGTATTTTCCGAACAATACTTCTGAGATTAGGCATTTTAAGGGAGCATTTTAG
TTATTTTCTCTTGCCTTTTTCTTTTCTGTATGCTGGTTTAACTGGTTTTACCGTTTCAGTCGTGCGTAGTTTACTACAAA
CTATCCTTGGTCAGTTTGGCTTTCGTAAGTGGGACAATTTAGGGCTAACGATGCTGATATTCTTTATCCTTTCACCTCAT
TTTTTAGAGACTGTGGGTGGTGTTTTATCCTTTGCTTATGCTTTTATCTTGTCAAGGCTTAACCTAGAATCACTATCCGG
TCGTCGCAAAGTAGTAGCTGAGAGTTTGGTTTTATCATTTGGTATTTTGCCCTTACTGATTTTTTATTTTGGGAGTTTTC
AACCCTTATCCATCCTCTTAACAGCCTGCTTTTCAGTGATTTTTGACGTGCTTTTGTTACCTCTGTTAAGTCTGGTATTA
TTAGCTAGTCCTTTGATGTCTTTGAGTTTCTGTAATCCTTTGTTTCTTGTTTTAGAGTCAGTCATCAAATGGACAGCTCA
GCTATCGCCAAAGCCTCTGGTTTTTGGTAGTCCTAACGTAGTAGTTCTTATCCTAATCCTTGCTTTTTTGGCTGCTTTAC
ATGACTTTTGGAAAGAAAAAAAGCTTAGATATGCCCTTTTATTAGCTAGCATCTGTTTGTTTGTTCTGACGAAACATCCT
TTGGAAAATGAAGTCACAGTTATGGATGTTGGGCAAGGGGACTCGATTTTGATTAGGGATATGGGAGGGAAAACGCTCCT
AATCGATACTGGTGGTCGAGTTGATTTTACACAGAAAGAAGCGTGGCGCAATCGACAGACAAGGGCTAATGCTGAAAAGA
CCTCGATTCCTTATTTGAAAAGTCGCGGTATTTCGACTATTGATCAACTGTTAATCACTCACACGGACACAGATCATATG
GGAGATCTAAGTATTTTAGCCAAGCATTTCAAAATTAAAGAAATTTTGATTAGTCCTGGGGCTATGACCAAGTCATCTTT
TGTGAAAGAGTTACAAGCATTAAACATAAAAGTGCGCTTGGTTCATGCAGGAGATCGGTTTCCTATTATGGGGACATCTC
TTCATGTTCTTTACCCATGGTCTCAGGGAGATGGCGGCAATAATGATTCTCTTGTTTTGTACGGTAAGTTACTTGATAAA
AGATTTCTTTTTACTGGTGATTTGGAAGTTGAAGGAGAAAAAGCCTTGCTTGCTAGATATCCAAACTTACCAGTGGATGT
TTTAAAAGCAGGTCATCATGGGTCTAAAGGCTCTTCTGATCCGGAGTTTTTGAGGCATATCAATGCCACAGAGGCCTTAA
TATCAGCAGGTCTGAATAATCGTTATCATCATCCCAATGATGAAACTTTGGAGCGGTTTGATGTCGAAAAGATGACAGTC
TATCGCACTGATCAAGAAGGCGCTATTCGTTATAGAGGTATGAAAAATTGGCGTGTTGAAACGGTACGATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (489-695)

• Domain of unknown function (DUF4131) (DUF4131) (28-173)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	49.046	98.789	0.485
comEC/celB	Streptococcus mitis SK321	48.844	98.923	0.483
comEC/celB	Streptococcus pneumoniae D39	48.027	98.923	0.475
comEC/celB	Streptococcus pneumoniae TIGR4	48.027	98.923	0.475
comEC/celB	Streptococcus pneumoniae R6	48.027	98.923	0.475
comEC/celB	Streptococcus pneumoniae Rx1	48.027	98.923	0.475
comEC	Lactococcus lactis subsp. cremoris KW2	44.173	99.327	0.439