Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   A0O21_RS02545 Genome accession   NZ_CP014699
Coordinates   527130..527840 (+) Length   236 a.a.
NCBI ID   WP_067060758.1    Uniprot ID   A0A172Q696
Organism   Streptococcus pantholopis strain TA 26     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 522130..532840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS02525 (A0O21_02535) - 523224..523874 (-) 651 WP_067060744.1 amino acid ABC transporter permease -
  A0O21_RS02530 (A0O21_02540) - 523960..524661 (-) 702 WP_067060747.1 amino acid ABC transporter permease -
  A0O21_RS02535 (A0O21_02545) - 525181..525990 (-) 810 WP_067060750.1 transporter substrate-binding domain-containing protein -
  A0O21_RS02540 (A0O21_02550) - 526002..526766 (-) 765 WP_067060753.1 amino acid ABC transporter ATP-binding protein -
  A0O21_RS02545 (A0O21_02555) vicR 527130..527840 (+) 711 WP_067060758.1 response regulator YycF Regulator
  A0O21_RS02550 (A0O21_02560) vicK 527833..529185 (+) 1353 WP_067060760.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A0O21_RS02555 (A0O21_02565) vicX 529188..529997 (+) 810 WP_067060763.1 MBL fold metallo-hydrolase Regulator
  A0O21_RS02560 (A0O21_02570) rnc 530824..531510 (+) 687 WP_067060766.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27062.92 Da        Isoelectric Point: 4.7070

>NTDB_id=173341 A0O21_RS02545 WP_067060758.1 527130..527840(+) (vicR) [Streptococcus pantholopis strain TA 26]
MKKILIVDDEKPISDIIKFNLAKEGYDTVTAFDGREALEKYGEESPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEENASTEMPEITIGELQILPDAFVALKRGTEVE
LTHREFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=173341 A0O21_RS02545 WP_067060758.1 527130..527840(+) (vicR) [Streptococcus pantholopis strain TA 26]
ATGAAGAAAATTCTTATCGTAGATGACGAGAAGCCAATTTCTGATATTATTAAGTTTAATTTGGCTAAGGAAGGTTATGA
TACAGTGACGGCCTTTGATGGCCGTGAAGCACTGGAAAAGTATGGGGAAGAAAGTCCGGATTTGATTATTCTCGATTTAA
TGCTGCCTGAACTGGATGGCTTAGAAGTTGCTAAAGAAGTGCGTAAGACCAGTCACATTCCGATTATTATGCTCTCTGCC
AAAGACAGTGAATTTGATAAGGTTATCGGTCTTGAAATCGGCGCGGATGACTATGTCACCAAGCCTTTCTCAAACCGCGA
ACTTCTGGCTAGGGTTAAGGCCCATTTACGCAGAACAGAAAACATTGAAACGGCGGTTGCGGAAGAGAACGCATCAACTG
AAATGCCAGAAATTACTATTGGTGAGCTGCAGATTTTACCAGACGCCTTTGTTGCTCTGAAACGCGGCACAGAAGTGGAA
CTGACTCACCGTGAGTTTGAATTGCTGCATCATTTAGCAACACATATCGGTCAAGTCATGACACGTGAACATTTACTTGA
GACGGTTTGGGGCTATGATTATTTTGGTGATGTCAGAACAGTCGATGTGACTGTGAGGCGTTTGCGTGAGAAAATTGAGG
ACACACCCAGCCGGCCGGAGTATATTTTGACCAGACGGGGTGTCGGATATTATATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q696

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

93.644

100

0.936
  micA Streptococcus pneumoniae Cp1015

77.35

99.153

0.767
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.352

98.729

0.458
  covR Streptococcus salivarius strain HSISS4

46.352

98.729

0.458
  scnR Streptococcus mutans UA159

38.627

98.729

0.381

Multiple sequence alignment