Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   A0O21_RS02550 Genome accession   NZ_CP014699
Coordinates   527833..529185 (+) Length   450 a.a.
NCBI ID   WP_067060760.1    Uniprot ID   A0A172Q671
Organism   Streptococcus pantholopis strain TA 26     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 522833..534185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS02525 (A0O21_02535) - 523224..523874 (-) 651 WP_067060744.1 amino acid ABC transporter permease -
  A0O21_RS02530 (A0O21_02540) - 523960..524661 (-) 702 WP_067060747.1 amino acid ABC transporter permease -
  A0O21_RS02535 (A0O21_02545) - 525181..525990 (-) 810 WP_067060750.1 transporter substrate-binding domain-containing protein -
  A0O21_RS02540 (A0O21_02550) - 526002..526766 (-) 765 WP_067060753.1 amino acid ABC transporter ATP-binding protein -
  A0O21_RS02545 (A0O21_02555) vicR 527130..527840 (+) 711 WP_067060758.1 response regulator YycF Regulator
  A0O21_RS02550 (A0O21_02560) vicK 527833..529185 (+) 1353 WP_067060760.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A0O21_RS02555 (A0O21_02565) vicX 529188..529997 (+) 810 WP_067060763.1 MBL fold metallo-hydrolase Regulator
  A0O21_RS02560 (A0O21_02570) rnc 530824..531510 (+) 687 WP_067060766.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51354.39 Da        Isoelectric Point: 4.7114

>NTDB_id=173342 A0O21_RS02550 WP_067060760.1 527833..529185(+) (vicK) [Streptococcus pantholopis strain TA 26]
MNNNIVGNLNTFEFAILLLLVFVAFYFIHLAIRDFRFSKNIRMLSDKVRDLITGNYTGDIKVSGDADMRDLAEHLNDLSK
VFQLTHENLAQEKNRLASILAYMTDGVLATDRTGQIIMINEMAQKQLNLSRDEALQLNIVDILGQDSPYNYSDLVSKTPE
IVLNQRNEYDEFITLRIRFALNRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQVTQLDIEMINFTAYMTSVLDRFDHIKNQESFGGKYYEIVRDYPAVP
IWIEIDTDKMTQVLDNIINNAIKYSPDGANITVSMKTTDTQLIISVADEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIVKQHQGFIWAKSDYGKGSTFTIVLPYEKSANIYEEWEEDGD

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=173342 A0O21_RS02550 WP_067060760.1 527833..529185(+) (vicK) [Streptococcus pantholopis strain TA 26]
ATGAATAATAATATCGTAGGAAATTTAAATACTTTTGAATTTGCTATCCTGCTTCTGCTTGTTTTTGTGGCATTTTATTT
TATTCATCTGGCTATCCGGGATTTTCGCTTCTCTAAAAATATCCGCATGCTTAGTGATAAGGTCAGAGACTTAATCACCG
GTAACTACACCGGTGATATTAAGGTCTCTGGAGATGCAGATATGAGAGATTTGGCTGAGCATCTCAATGATTTGTCCAAA
GTTTTTCAGCTGACTCATGAAAATTTAGCCCAAGAAAAAAATCGCTTAGCCAGTATTCTGGCTTATATGACTGATGGGGT
GCTGGCAACAGACCGAACCGGGCAAATTATAATGATTAATGAAATGGCGCAGAAGCAGCTGAATTTAAGCCGTGATGAAG
CCCTTCAGCTGAATATTGTAGATATTTTAGGGCAGGACAGTCCCTATAATTACAGCGACTTGGTATCAAAGACACCGGAG
ATTGTTTTAAATCAGCGCAATGAGTACGATGAATTTATAACGCTGCGTATCCGATTTGCTCTTAACCGGCGTGAAAGCGG
CTTTATTTCAGGTTTGGTTGCTGTTTTACATGACACAACAGAACAGGAAAAGGAGGAGCGTGAGCGTCGGCTGTTTGTTT
CCAATGTCAGCCATGAGCTGAGAACTCCTCTGACTTCAGTAAAATCTTATTTGGAGGCGCTGGATGAAGGAGCGCTGAAA
GAGGATATTGCGCCCAGCTTTATCAAGGTTTCTCTGGATGAAACCAATCGGATGATACGGATGATTTCGGACTTGCTCAA
TTTATCCAGAATCGATAATCAGGTCACGCAGTTAGACATTGAAATGATTAATTTTACTGCTTATATGACCTCTGTTTTAG
ACCGATTTGACCACATTAAGAATCAGGAGAGTTTTGGCGGAAAATATTATGAAATTGTCAGAGACTATCCTGCTGTGCCT
ATTTGGATTGAAATCGATACAGACAAGATGACACAGGTGCTGGACAATATTATCAACAATGCCATAAAATATTCTCCGGA
CGGAGCCAATATCACCGTCAGTATGAAAACGACAGATACACAGCTGATTATTTCTGTCGCTGATGAAGGCCTGGGAATTC
CTAAAAAAGATCTGCCTCTGATTTTTGACCGCTTTTACCGAGTAGATAAAGCAAGGAGCCGAGCTCAGGGAGGGACAGGC
CTGGGGTTGGCTATTGCCAAGGAAATTGTTAAGCAGCATCAGGGATTTATTTGGGCTAAAAGTGATTATGGCAAAGGGTC
GACCTTTACCATTGTTTTACCATATGAAAAGTCTGCTAATATTTATGAAGAATGGGAGGAAGACGGCGACTGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

PAS fold (PAS)

(95-184)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q671

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.272

91.556

0.68
  micB Streptococcus pneumoniae Cp1015

63.636

95.333

0.607

Multiple sequence alignment