Detailed information NTG0170332

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BKM66_RS04410
• Genome accession: NZ_CP017666
• Coordinates: 888220..888891 (+)
• Length: 223 a.a.
• NCBI ID: WP_024385291.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 0061
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 883220..893891

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKM66_RS04380 (BKM66_04280)	pstC	883312..884229 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
BKM66_RS04385 (BKM66_04285)	pstA	884219..885106 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
BKM66_RS04390 (BKM66_04290)	pstB	885131..885934 (+)	804	WP_029185151.1	phosphate ABC transporter ATP-binding protein PstB	-
BKM66_RS04395 (BKM66_04295)	pstB	885946..886704 (+)	759	WP_105184039.1	phosphate ABC transporter ATP-binding protein PstB	-
BKM66_RS04400 (BKM66_04300)	phoU	886731..887387 (+)	657	WP_024413748.1	phosphate signaling complex protein PhoU	-
BKM66_RS04405 (BKM66_04305)	-	887553..888026 (+)	474	WP_105184038.1	hypothetical protein	-
BKM66_RS04410 (BKM66_04310)	ciaR	888220..888891 (+)	672	WP_024385291.1	response regulator transcription factor	Regulator
BKM66_RS04415 (BKM66_04315)	ciaH	888884..890263 (+)	1380	WP_105184037.1	HAMP domain-containing sensor histidine kinase	Regulator
BKM66_RS04420 (BKM66_04320)	-	890364..891593 (+)	1230	WP_044679497.1	transglutaminase domain-containing protein	-
BKM66_RS04425 (BKM66_04325)	rpsT	891856..892104 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
BKM66_RS04430 (BKM66_04330)	coaA	892163..893083 (-)	921	WP_002935283.1	type I pantothenate kinase	-
BKM66_RS04435 (BKM66_04335)	-	893192..893782 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25231.80 Da
• Isoelectric Point: 4.2183

>NTDB_id=170332 BKM66_RS04410 WP_024385291.1 888220..888891(+) (ciaR) [Streptococcus suis strain 0061]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=170332 BKM66_RS04410 WP_024385291.1 888220..888891(+) (ciaR) [Streptococcus suis strain 0061]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGCCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACCCCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCATTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCAGGTAAGTTTAATGAAAATACACTAACTTATGGGGACGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGCGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTCGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTACCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.789	100	0.888
ciaR	Streptococcus pneumoniae D39	88.789	100	0.888
ciaR	Streptococcus pneumoniae R6	88.789	100	0.888
ciaR	Streptococcus pneumoniae TIGR4	88.789	100	0.888
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.368