Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BKM66_RS04415 Genome accession   NZ_CP017666
Coordinates   888884..890263 (+) Length   459 a.a.
NCBI ID   WP_105184037.1    Uniprot ID   -
Organism   Streptococcus suis strain 0061     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 883884..895263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS04385 (BKM66_04285) pstA 884219..885106 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  BKM66_RS04390 (BKM66_04290) pstB 885131..885934 (+) 804 WP_029185151.1 phosphate ABC transporter ATP-binding protein PstB -
  BKM66_RS04395 (BKM66_04295) pstB 885946..886704 (+) 759 WP_105184039.1 phosphate ABC transporter ATP-binding protein PstB -
  BKM66_RS04400 (BKM66_04300) phoU 886731..887387 (+) 657 WP_024413748.1 phosphate signaling complex protein PhoU -
  BKM66_RS04405 (BKM66_04305) - 887553..888026 (+) 474 WP_105184038.1 hypothetical protein -
  BKM66_RS04410 (BKM66_04310) ciaR 888220..888891 (+) 672 WP_024385291.1 response regulator transcription factor Regulator
  BKM66_RS04415 (BKM66_04315) ciaH 888884..890263 (+) 1380 WP_105184037.1 HAMP domain-containing sensor histidine kinase Regulator
  BKM66_RS04420 (BKM66_04320) - 890364..891593 (+) 1230 WP_044679497.1 transglutaminase domain-containing protein -
  BKM66_RS04425 (BKM66_04325) rpsT 891856..892104 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  BKM66_RS04430 (BKM66_04330) coaA 892163..893083 (-) 921 WP_002935283.1 type I pantothenate kinase -
  BKM66_RS04435 (BKM66_04335) - 893192..893782 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  BKM66_RS04440 (BKM66_04340) - 893779..895056 (+) 1278 WP_024385288.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51990.69 Da        Isoelectric Point: 6.8979

>NTDB_id=170333 BKM66_RS04415 WP_105184037.1 888884..890263(+) (ciaH) [Streptococcus suis strain 0061]
MPKRIRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIKLATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKIFVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=170333 BKM66_RS04415 WP_105184037.1 888884..890263(+) (ciaH) [Streptococcus suis strain 0061]
ATGCCTAAGCGAATCAGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCGACTATGTATCAAAATTCCGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTAAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAGATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAACAA
AAGGACTTTGTCGAAAATGCTAGTCATGAGTTGCGTACGCCGCTGGCTGTTCTCCAAAATCGTTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTCACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACACGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTTTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

50.11

99.129

0.497
  ciaH Streptococcus pneumoniae Rx1

49.244

100

0.497
  ciaH Streptococcus pneumoniae D39

49.244

100

0.497
  ciaH Streptococcus pneumoniae R6

49.244

100

0.497
  ciaH Streptococcus pneumoniae TIGR4

49.244

100

0.497

Multiple sequence alignment