Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   AXE83_RS06240 Genome accession   NZ_CP014264
Coordinates   1330178..1331041 (-) Length   287 a.a.
NCBI ID   WP_060955816.1    Uniprot ID   A0A0X8JYG7
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1325178..1336041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS06220 (AXE83_06220) - 1325932..1326588 (-) 657 WP_060955813.1 MmcQ/YjbR family DNA-binding protein -
  AXE83_RS06225 (AXE83_06225) - 1326632..1327264 (-) 633 WP_060955814.1 copper homeostasis protein CutC -
  AXE83_RS06230 (AXE83_06230) - 1327358..1327717 (-) 360 WP_045763427.1 YbaN family protein -
  AXE83_RS06235 (AXE83_06235) topA 1327972..1330059 (-) 2088 WP_060955815.1 type I DNA topoisomerase -
  AXE83_RS06240 (AXE83_06240) dprA/cilB/dalA 1330178..1331041 (-) 864 WP_060955816.1 DNA-processing protein DprA Machinery gene
  AXE83_RS06245 (AXE83_06245) dapA 1331142..1332077 (-) 936 WP_060955817.1 4-hydroxy-tetrahydrodipicolinate synthase -
  AXE83_RS06250 (AXE83_06250) - 1332128..1333204 (-) 1077 WP_049504392.1 aspartate-semialdehyde dehydrogenase -
  AXE83_RS06255 (AXE83_06255) - 1333492..1334241 (-) 750 WP_000078698.1 class A sortase -

Sequence

Protein


Download         Length: 287 a.a.        Molecular weight: 32087.96 Da        Isoelectric Point: 5.9217

>NTDB_id=170001 AXE83_RS06240 WP_060955816.1 1330178..1331041(-) (dprA/cilB/dalA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MKIKIDNFEIYKLKQAGLSNQQVLKVLQYGEIYDQELTLETIAEASECRNPVVFMERYHKLTFESMERLRSDFEKFPSFS
ILDDIYPFTLSEIYDAPVLLFYKGDLKLLKLPKIAVVGSRSCSQTGTKSVRKVIEELENDLVIVSGLARGIDTAAHMSIL
QGGGKTIAVIGTGLDVYYPRSNKRLQDYIGQHHLLLSEYGPGEEPLKYHFPARNRIIAGLCMGVIVAEAKMRSGSLITCE
RAMEEGRDVFAIPGSILDGRSDGCHHLVQEGAKLVSSGQDVLAEFEF

Nucleotide


Download         Length: 864 bp        

>NTDB_id=170001 AXE83_RS06240 WP_060955816.1 1330178..1331041(-) (dprA/cilB/dalA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGAAAATTAAGATTGATAATTTTGAGATTTATAAGTTGAAACAAGCAGGTTTAAGTAATCAACAGGTTTTAAAGGTACT
TCAATATGGAGAAATTTATGATCAAGAATTAACCCTAGAAACGATAGCAGAAGCATCTGAGTGTAGAAATCCAGTGGTTT
TTATGGAACGTTACCATAAACTCACCTTTGAAAGTATGGAGAGATTAAGAAGTGACTTTGAAAAATTTCCCTCATTTTCC
ATCCTAGACGATATCTATCCCTTTACTCTCAGTGAAATCTATGATGCTCCAGTATTATTATTTTATAAGGGCGATTTAAA
ACTCTTAAAGTTGCCTAAGATTGCAGTTGTAGGCAGTCGCTCTTGTAGTCAAACAGGGACAAAATCGGTCCGCAAGGTTA
TTGAAGAACTGGAGAATGATCTGGTGATTGTGAGTGGGCTTGCTAGAGGGATTGATACTGCAGCTCATATGTCTATTCTT
CAAGGTGGTGGAAAAACTATTGCTGTCATTGGTACTGGCTTAGATGTCTACTATCCTAGATCGAATAAACGTTTGCAGGA
CTACATCGGTCAACATCACCTGCTCCTCAGTGAATATGGGCCTGGTGAAGAACCTTTGAAATATCATTTTCCAGCAAGAA
ATCGGATTATTGCTGGCCTATGTATGGGTGTTATCGTTGCTGAAGCAAAGATGAGATCTGGTAGTTTGATTACCTGTGAG
CGAGCTATGGAAGAAGGAAGAGATGTTTTTGCTATTCCAGGTAGCATTTTAGATGGTCGTTCAGATGGTTGTCATCACTT
GGTTCAAGAAGGCGCAAAACTTGTTTCGAGTGGTCAGGACGTGCTAGCAGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(5-62)

DNA recombination-mediator protein A (DNA_processg_A)

(81-276)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JYG7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

78.596

99.303

0.78
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

78.246

99.303

0.777
  dprA/cilB/dalA Streptococcus pneumoniae D39

78.246

99.303

0.777
  dprA/cilB/dalA Streptococcus pneumoniae R6

78.246

99.303

0.777
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

78.246

99.303

0.777
  dprA/cilB/dalA Streptococcus mitis SK321

77.544

99.303

0.77
  dprA Streptococcus mutans UA159

61.131

98.606

0.603
  dprA Lactococcus lactis subsp. cremoris KW2

54.804

97.909

0.537
  dprA Legionella pneumophila strain ERS1305867

51.232

70.732

0.362

Multiple sequence alignment