Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AU077_RS04475 Genome accession   NZ_CP013688
Coordinates   890718..891392 (+) Length   224 a.a.
NCBI ID   WP_014294586.1    Uniprot ID   A0A380K9T7
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 885718..896392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS04465 (AU077_04465) - 886420..887676 (-) 1257 WP_014295262.1 ISL3 family transposase -
  AU077_RS04470 (AU077_04470) - 887977..890520 (+) 2544 WP_039670833.1 M1 family metallopeptidase -
  AU077_RS04475 (AU077_04475) ciaR 890718..891392 (+) 675 WP_014294586.1 response regulator transcription factor Regulator
  AU077_RS04480 (AU077_04480) ciaH 891382..892722 (+) 1341 WP_058621635.1 sensor histidine kinase Regulator
  AU077_RS04485 (AU077_04485) rpsT 892860..893111 (-) 252 WP_081498578.1 30S ribosomal protein S20 -
  AU077_RS04490 (AU077_04490) coaA 893186..894106 (-) 921 WP_058621636.1 type I pantothenate kinase -
  AU077_RS04495 (AU077_04495) - 894220..894813 (+) 594 WP_058621637.1 class I SAM-dependent methyltransferase -
  AU077_RS04500 (AU077_04500) deoC 895305..895967 (+) 663 WP_058621638.1 deoxyribose-phosphate aldolase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25525.27 Da        Isoelectric Point: 4.3477

>NTDB_id=164048 AU077_RS04475 WP_014294586.1 890718..891392(+) (ciaR) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGVSTPVLIMTA
KESLGDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKYNFNTLSYEELTVDTSTNTTIANGKEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKDTTFAKNLQTLRSVGYILKNVE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=164048 AU077_RS04475 WP_014294586.1 890718..891392(+) (ciaR) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGATTAAGATATTATTAGTAGAGGATGATTTGAGTCTATCTAATTCCATTTTTGATTTTTTAGATGATTTTGCAGATGT
TATGCAGGTATTTGACGGCGAAGAAGGTTTGTACGAAGCTGAAAGTGGCGTATATGACCTTATTTTGCTTGACTTGATGT
TACCTGAAAAAGATGGTTTCCAAGTGCTTAAAGAGTTACGAGAAAAAGGTGTGTCAACACCAGTACTTATTATGACTGCC
AAAGAAAGTCTTGGTGATAAGGGACATGGTTTCGAGTTGGGAGCAGATGATTATCTTACTAAACCATTTTACCTTGAAGA
GCTAAAAATGCGTATTCAAGCTCTTTTAAAACGTTCGGGTAAATACAACTTCAATACCTTATCTTATGAAGAATTAACCG
TTGACACTTCTACCAATACAACAATAGCTAACGGTAAAGAAGTCGAGCTGCTTGGTAAAGAATTTGATTTGTTGGTTTAT
TTCTTACAAAATCAAAATGTTATTTTACCAAAATCACAAATTTTTGACCGTATTTGGGGCTTTGATAGTGATACAACGAT
TTCGGTTGTTGAAGTTTACGTTTCAAAAATTCGAAAAAAACTCAAAGACACCACCTTTGCCAAAAATCTTCAAACCCTAC
GGAGTGTAGGTTATATTCTGAAAAATGTTGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380K9T7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.377

99.554

0.92
  ciaR Streptococcus pneumoniae Rx1

86.607

100

0.866
  ciaR Streptococcus pneumoniae D39

86.607

100

0.866
  ciaR Streptococcus pneumoniae R6

86.607

100

0.866
  ciaR Streptococcus pneumoniae TIGR4

86.607

100

0.866
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.938

100

0.393
  vicR Streptococcus mutans UA159

36.017

100

0.379
  micA Streptococcus pneumoniae Cp1015

35.193

100

0.366

Multiple sequence alignment