Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   AU077_RS04480 Genome accession   NZ_CP013688
Coordinates   891382..892722 (+) Length   446 a.a.
NCBI ID   WP_058621635.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 886382..897722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS04465 (AU077_04465) - 886420..887676 (-) 1257 WP_014295262.1 ISL3 family transposase -
  AU077_RS04470 (AU077_04470) - 887977..890520 (+) 2544 WP_039670833.1 M1 family metallopeptidase -
  AU077_RS04475 (AU077_04475) ciaR 890718..891392 (+) 675 WP_014294586.1 response regulator transcription factor Regulator
  AU077_RS04480 (AU077_04480) ciaH 891382..892722 (+) 1341 WP_058621635.1 sensor histidine kinase Regulator
  AU077_RS04485 (AU077_04485) rpsT 892860..893111 (-) 252 WP_081498578.1 30S ribosomal protein S20 -
  AU077_RS04490 (AU077_04490) coaA 893186..894106 (-) 921 WP_058621636.1 type I pantothenate kinase -
  AU077_RS04495 (AU077_04495) - 894220..894813 (+) 594 WP_058621637.1 class I SAM-dependent methyltransferase -
  AU077_RS04500 (AU077_04500) deoC 895305..895967 (+) 663 WP_058621638.1 deoxyribose-phosphate aldolase -
  AU077_RS04505 (AU077_04505) - 896156..897220 (+) 1065 WP_082306732.1 BMP family lipoprotein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50232.13 Da        Isoelectric Point: 6.0240

>NTDB_id=164049 AU077_RS04480 WP_058621635.1 891382..892722(+) (ciaH) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNGNDYVVRTMERSDTLQSNDSPTD
TFSGGTSSSGKAKPSTSRVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEGSVGEIKEQKITTIFGQTEKYHVLTV
KVSSSEYPSIKYATFLVSVRQLDEASERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKTFVENASHELRTP
LTVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPPTFNEIFENYDMIAEENG
KTFVGHNLVDRPIKSDRTLLKQLMTILFDNAIKYTDDDGVIEFTVKTTDKQTILTVADNGPGISEADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=164049 AU077_RS04480 WP_058621635.1 891382..892722(+) (ciaH) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGTTGAATAAATTACAGAAAAAATTATCATCAGGGACATTTTCACATTTCTTCCATTTCTTTGCTGTCTTCACGGGAAT
TTTTGTCATCATGACAGTTATCATTTTGCAGATTATGCGCTATGGTCTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGGCAATGATTATGTCGTGCGAACTATGGAACGTAGCGATACTTTGCAATCGAATGATTCTCCTACGGAC
ACTTTTTCAGGAGGAACAAGTAGTTCTGGGAAAGCGAAACCTAGTACCAGCAGAGTTGGTCTAAGTAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATCTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACGTTATCGACAACTTTTGATG
AAGGTAGTGTCGGCGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATACCATGTGCTGACTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGTGTTCGTCAGTTAGATGAAGCTAGCGA
ACGATATGTAACAATTACGATCACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAAACCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTACTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCTGATGCTACAATTTTGGATAATAGTGAAAGTATTGC
CGCCAGTTTAGACGAAGTTCGAAATATGCGAATTTTGACCACAAATCTGCTGAATTTGGCACGTCGTGATGATGGTTTGA
AAGTTGAGTTGGAGGATATTCAACCACCGACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACATTTGTCGGACATAATTTGGTAGACCGACCAATCAAATCAGATCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATACACCGACGATGATGGTGTCATTGAATTTACCGTTAAAACAACAGACAAACAAACAATTC
TGACAGTTGCTGATAACGGTCCAGGAATTAGCGAAGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGCGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGACGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTCCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.594

99.327

0.592
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511

Multiple sequence alignment