Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ATM98_RS01490 Genome accession   NZ_CP013651
Coordinates   286441..287115 (+) Length   224 a.a.
NCBI ID   WP_006596563.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 281441..292115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS01470 (ATM98_01470) phoU 281603..282256 (+) 654 WP_061563818.1 phosphate signaling complex protein PhoU -
  ATM98_RS01475 (ATM98_01475) - 282388..284931 (+) 2544 WP_061563819.1 M1 family metallopeptidase -
  ATM98_RS01480 (ATM98_01480) - 284986..285528 (-) 543 WP_061563820.1 biotin transporter BioY -
  ATM98_RS01485 (ATM98_01485) - 285738..286328 (+) 591 WP_061563821.1 hypothetical protein -
  ATM98_RS01490 (ATM98_01490) ciaR 286441..287115 (+) 675 WP_006596563.1 response regulator transcription factor Regulator
  ATM98_RS01495 (ATM98_01495) ciaH 287105..288478 (+) 1374 WP_061563822.1 HAMP domain-containing sensor histidine kinase Regulator
  ATM98_RS01500 (ATM98_01500) - 288727..289113 (+) 387 WP_023022851.1 VOC family protein -
  ATM98_RS01505 (ATM98_01505) - 289329..290693 (+) 1365 WP_237367531.1 polysaccharide deacetylase family protein -
  ATM98_RS01510 (ATM98_01510) - 290726..291814 (-) 1089 WP_061563824.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25324.05 Da        Isoelectric Point: 4.3320

>NTDB_id=163395 ATM98_RS01490 WP_006596563.1 286441..287115(+) (ciaR) [Streptococcus sp. A12]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKELRDKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKVNENTLSYGNVTVNLSTNSTLVEGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFAKNLQTLRSVGYILKDAQ

Nucleotide


Download         Length: 675 bp        

>NTDB_id=163395 ATM98_RS01490 WP_006596563.1 286441..287115(+) (ciaR) [Streptococcus sp. A12]
ATGATTAAGATTCTATTAGTCGAAGACGACCTCGGTTTGTCTAATTCAGTATTTGATTTTTTAGATGACTTTGCAGATGT
CATGCAGGTCTTTGATGGAGACGAAGGCCTTTATGAGGCTGAAAGTGGCATCTATGACCTCATTTTGCTAGATCTCATGC
TCCCTGAAAAAGATGGTTTCCAAGTTCTGAAAGAATTGAGAGATAAGGGTGTTTCCACTCCAGTATTGATTATGACAGCC
AAAGAGAGTTTGGACGATAAGGGCCATGGATTTGAGTTAGGAGCAGATGACTACCTGACCAAGCCATTCTACCTAGAAGA
ACTCAAGATGCGAATCCAAGCATTGTTGAAGCGCTCTGGTAAGGTCAATGAAAATACCCTATCTTATGGAAATGTAACCG
TTAATCTCTCGACAAACTCTACCCTTGTTGAAGGGAAAGAAGTGGAGCTATTAGGGAAAGAATTTGACCTTTTGGTTTAT
TTCCTTCAAAATCAAAATGTTATCTTGCCAAAAACACAAATCTTTGATCGACTTTGGGGATTTGATAGTGATACGACTAT
CTCGGTTGTTGAAGTGTATGTTTCTAAGATTCGTAAGAAGTTAAAAGGAACAGACTTTGCAAAAAATCTCCAAACATTGC
GTAGCGTGGGGTACATTCTGAAAGATGCTCAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

90.625

100

0.906
  ciaR Streptococcus pneumoniae D39

90.625

100

0.906
  ciaR Streptococcus pneumoniae R6

90.625

100

0.906
  ciaR Streptococcus pneumoniae TIGR4

90.625

100

0.906
  ciaR Streptococcus mutans UA159

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.428

100

0.393
  vicR Streptococcus mutans UA159

35.622

100

0.371
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.362

Multiple sequence alignment